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NCT07579429 · ClinicalTrials.gov registry record · Phase 2
Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial)
A Phase 2 study, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 10
- Enrollment target
NCT07579429: Recruiting Phase 2 study, sponsored by University of Colorado, Denver.
NCT07579429 is a Phase 2 study that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 10 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07579429, a Phase 2 study, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 10 participants
- Enrollment target
Study Summary
This is an open-label, phase 2 study for lower risk MDS and high risk CCUS patients who are transfusion independent. There will be two cohorts enrolled at the same time to measure the effect of nicotinamide riboside and pterostilbene at different doses. The primary goals of the study are: * to assess if study drug improves cytopenias in patients * to determine safety of the study drug in patients
Primary Outcome
To assess efficacy of nicotinamide riboside and pterostilbene supplementation by assessing whether it increased hemoglobin by 1g/dL in 24 weeks.
Interventions
- DRUG Nicotinamide Riboside
- DRUG Pterostilbene
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2026-05-20 |
| Est. Completion | 2030-12-18 |
| Phase | Phase 2 |
What NCT07579429 shows while recruiting
NCT07579429 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 2 interventions - of which Nicotinamide Riboside is the first listed.
NCT07579429 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07579429 about?
NCT07579429 is a clinical study titled "Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial)". This is an open-label, phase 2 study for lower risk MDS and high risk CCUS patients who are transfusion independent. There will be two cohorts enrolled at the same time to measure the effect of nicotinamide riboside and pterostilbene at different doses. The primary goals of the study are: * to asse...
What is the current status of trial NCT07579429?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 2026-05-20. Estimated completion is 2030-12-18.
What interventions are being tested in trial NCT07579429?
The interventions under investigation include: Nicotinamide Riboside (DRUG), Pterostilbene (DRUG).
Who is sponsoring clinical trial NCT07579429?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07579429's enrollment target sits among peer trials
10 1968th of 2000 higher than 12 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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