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NCT07577947 · ClinicalTrials.gov registry record · NA

Health And Response: Digital Markers for Outcomes in Perinatal Depression Treatment Study

A NA study, sponsored by University of California, Los Angeles.

Recruiting
Registry status
NA
Development phase
250
Enrollment target

NCT07577947: Recruiting NA study, sponsored by University of California, Los Angeles.

NCT07577947 is a NA study that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 250 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07577947, a NA study, is actively recruiting participants, sponsored by University of California, Los Angeles.

RECRUITING
Registry status
NA
Development phase
250 participants
Enrollment target

Study Summary

The purpose of this study is to determine if the addition of digital sensing data collected from phones and watches during the early stages of perinatal depression (PND) treatment can better predict treatment outcomes than using self-reported symptoms alone.STAND for PND: The UCLA Depression Grand Challenge (DGC) has previously developed a technology-assisted, scalable therapy system called STAND (Screening and Treatment for ANxiety and Depression) for perinatal depression (PND) and has demonstrated in an initial randomized clinical trial that this treatment intervention to be as effective as psychiatrist delivered care for PND. In this study, the investigators will administer STAND for PND for up to 12 weeks as part of study participation. There will be no comparison between our treatment intervention and a treatment as usual condition, as this is not a trial of efficacy. In the STAND for PND treatment model, women with moderate symptoms will be routed to coach-guided, digital cognitive behavioral therapy (CBT) tailored to PND, which has been demonstrated to be an effective treatment approach for PND. Women with severe depression or suicidality will be routed to clinician delivered CBT, with pharmacotherapy as needed, with both CBT and pharmacotherapy demonstrated to be effective treatment approaches for PND. Symptoms will be regularly monitored throughout the intervention period. Digital Sensing in Depression: The DGC also has substantial experience in large-scale longitudinal digital sensing studies, and experience identifying associations between self-report or clinical ratings of depressive symptoms and digital sensing features, including in pregnant and postpartum women. Digital Sensing in a STAND for PND study: In our previous STAND for PND study, the investigators did not include digital sensing. In this next phase of our research program, the investigators will collect digital sensing data from phones and watches during the first four weeks of study partici

Primary Outcome

Self-reported depression symptom severity scores

Interventions

  • BEHAVIORAL Perinatal depression online cognitive-behavioral therapy course
  • BEHAVIORAL Clinical care (psychotherapy sessions)

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2026-05-01
Est. Completion 2027-05-01
Phase NA

What NCT07577947 shows while recruiting

NCT07577947 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower).

The record links to 0 conditions, and to 2 interventions - of which Perinatal depression online cognitive-behavioral therapy course is the first listed.

NCT07577947 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07577947 about?

NCT07577947 is a clinical study titled "Health And Response: Digital Markers for Outcomes in Perinatal Depression Treatment Study". The purpose of this study is to determine if the addition of digital sensing data collected from phones and watches during the early stages of perinatal depression (PND) treatment can better predict treatment outcomes than using self-reported symptoms alone.STAND for PND: The UCLA Depression Grand C...

What is the current status of trial NCT07577947?

This trial is currently recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2026-05-01. Estimated completion is 2027-05-01.

What interventions are being tested in trial NCT07577947?

The interventions under investigation include: Perinatal depression online cognitive-behavioral therapy course (BEHAVIORAL), Clinical care (psychotherapy sessions) (BEHAVIORAL).

Who is sponsoring clinical trial NCT07577947?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07577947's enrollment target sits among peer trials

250 410th of 2000 higher than 1,567 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07577947, the US trial registry maintained by the National Library of Medicine. NCT07577947 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.