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NCT07575932 · ClinicalTrials.gov registry record · Phase 2

A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

A Phase 2 study, sponsored by Pfizer.

Recruiting
Registry status
Phase 2
Development phase
872
Enrollment target

NCT07575932: Recruiting Phase 2 study, sponsored by Pfizer.

NCT07575932 is a Phase 2 study that is actively recruiting participants, run by Pfizer. The registered enrollment target is 872 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (556% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07575932, a Phase 2 study, is actively recruiting participants, sponsored by Pfizer.

RECRUITING
Registry status
Phase 2
Development phase
872 participants
Enrollment target

Study Summary

This study is being done to learn about the safety and effects of the study drugs, PF-08653945 and PF-08653944, when given alone or together for weight loss, compared to a placebo (a dummy drug that has no active ingredient in it).

Interventions

  • DRUG Placebo
  • DRUG PF-08653944
  • DRUG PF-08653945

Trial Details

FieldValue
Enrollment Target 872 participants
Start Date 2026-05-11
Est. Completion 2028-01-05
Phase Phase 2
Pfizer

1,845 total trials

What NCT07575932 shows while recruiting

NCT07575932 is an interventional study that assigns participants to a tested intervention. The registered 872 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (556% higher).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT07575932 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07575932 about?

NCT07575932 is a clinical study titled "A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)". This study is being done to learn about the safety and effects of the study drugs, PF-08653945 and PF-08653944, when given alone or together for weight loss, compared to a placebo (a dummy drug that has no active ingredient in it).

What is the current status of trial NCT07575932?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 872 participants. The study started on 2026-05-11. Estimated completion is 2028-01-05.

What interventions are being tested in trial NCT07575932?

The interventions under investigation include: Placebo (DRUG), PF-08653944 (DRUG), PF-08653945 (DRUG).

Who is sponsoring clinical trial NCT07575932?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07575932's enrollment target sits among peer trials

872 33rd of 2000 higher than 1,968 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07575932, the US trial registry maintained by the National Library of Medicine. NCT07575932 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.