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NCT07572266 · ClinicalTrials.gov registry record · NA

Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults

A NA study, sponsored by Florida Institute for Human and Machine Cognition.

Not yet
Registry status
NA
Development phase
226
Enrollment target

NCT07572266: Clinical Trial NA study, sponsored by Florida Institute for Human and Machine Cognition.

NCT07572266 is a NA study that has not yet begun recruiting, run by Florida Institute for Human and Machine Cognition. The registered enrollment target is 226 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (84% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07572266, a NA study, has not yet begun recruiting, sponsored by Florida Institute for Human and Machine Cognition.

NOT YET RECRUITING
Registry status
NA
Development phase
226 participants
Enrollment target

Study Summary

Aging-related functional declines are thought to be caused by hallmark biological processes that ultimately manifest in physical, mental, and metabolic impairments to compromise intrinsic capacity and healthspan. Exercise is the only multipotent treatment with promise to mitigate many of the aging hallmarks, but there is substantial variability in individual exercise responsiveness. Thus, the investigators approach to boosting exercise responsiveness in aging is to combine an exercise training prescription containing both endurance and resistance training (in alignment with DHHS guidelines) with a nitrate-enriched dietary supplement to augment the cellular, tissue, and systemic adaptations that induce myriad health benefits of exercise in older adults.

Primary Outcome

The primary outcome will be assessed using logistic regression with the proportion not attaining Cardiorespiratory Fitness and functional Muscle Quality Minimally Clinical Differences as the response variable and treatment adjusted for sex and age group across the 12 week intervention.

Interventions

  • DIETARY_SUPPLEMENT Nitrate depleted beetroot juice
  • DIETARY_SUPPLEMENT Nitrate enriched beetroot juice
  • OTHER 12 week of combined exercise training

Trial Details

FieldValue
Enrollment Target 226 participants
Start Date 2026-07
Est. Completion 2031-05
Phase NA

What is known before NCT07572266 opens enrollment

NCT07572266 is an interventional study that assigns participants to a tested intervention. The registered 226 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (84% lower).

The record links to 0 conditions, and to 3 interventions - of which Nitrate depleted beetroot juice is the first listed.

NCT07572266 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07572266 about?

NCT07572266 is a clinical study titled "Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults". Aging-related functional declines are thought to be caused by hallmark biological processes that ultimately manifest in physical, mental, and metabolic impairments to compromise intrinsic capacity and healthspan. Exercise is the only multipotent treatment with promise to mitigate many of the aging h...

What is the current status of trial NCT07572266?

This trial is currently not yet recruiting. It is a NA study. The enrollment target is 226 participants. The study started on 2026-07. Estimated completion is 2031-05.

What interventions are being tested in trial NCT07572266?

The interventions under investigation include: Nitrate depleted beetroot juice (DIETARY_SUPPLEMENT), Nitrate enriched beetroot juice (DIETARY_SUPPLEMENT), 12 week of combined exercise training (OTHER).

Who is sponsoring clinical trial NCT07572266?

This trial is sponsored by Florida Institute for Human and Machine Cognition, which has 7 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07572266's enrollment target sits among peer trials

226 471st of 2000 higher than 1,529 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07572266, the US trial registry maintained by the National Library of Medicine. NCT07572266 (mid enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.