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NCT07570953 · ClinicalTrials.gov registry record · Phase 2

A Study Of Synthetic THC And Sleep

A Phase 2 study, sponsored by Mayo Clinic.

Not yet
Registry status
Phase 2
Development phase
72
Enrollment target

NCT07570953: Clinical Trial Phase 2 study, sponsored by Mayo Clinic.

NCT07570953 is a Phase 2 study that has not yet begun recruiting, run by Mayo Clinic. The registered enrollment target is 72 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (46% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT07570953, a Phase 2 study, has not yet begun recruiting, sponsored by Mayo Clinic.

NOT YET RECRUITING
Registry status
Phase 2
Development phase
72 participants
Enrollment target

Study Summary

The purpose of this study is to determine if oral dronabinol prior to sleep can improve CPAP adherence and sleep quality in humans. We also seek to determine if combination therapy of CPAP and pre-sleep dronabinol is associated with improved BP regulation. We will also explore BP regulatory mechanisms and whether these are impacted differently between traditional CPAP therapy and combination CPAP/dronabinol.

Primary Outcome

CPAP therapy is defined as using the therapeutic device for ≥ 4 hours per night

Interventions

  • DRUG Placebo
  • DRUG Dronabinol

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2026-04
Est. Completion 2028-04
Phase Phase 2
Mayo Clinic

2,844 total trials

What is known before NCT07570953 opens enrollment

NCT07570953 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (46% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT07570953 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07570953 about?

NCT07570953 is a clinical study titled "A Study Of Synthetic THC And Sleep". The purpose of this study is to determine if oral dronabinol prior to sleep can improve CPAP adherence and sleep quality in humans. We also seek to determine if combination therapy of CPAP and pre-sleep dronabinol is associated with improved BP regulation. We will also explore BP regulatory mechanis...

What is the current status of trial NCT07570953?

This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 72 participants. The study started on 2026-04. Estimated completion is 2028-04.

What interventions are being tested in trial NCT07570953?

The interventions under investigation include: Placebo (DRUG), Dronabinol (DRUG).

Who is sponsoring clinical trial NCT07570953?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07570953's enrollment target sits among peer trials

72 925th of 2000 higher than 1,065 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07570953, the US trial registry maintained by the National Library of Medicine. NCT07570953 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.