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NCT07568145 · ClinicalTrials.gov registry record · NA

The PREVENT Resilience Study

A NA study, sponsored by Emory University.

Recruiting
Registry status
NA
Development phase
50
Enrollment target

NCT07568145: Recruiting NA study, sponsored by Emory University.

NCT07568145 is a NA study that is actively recruiting participants, run by Emory University. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07568145, a NA study, is actively recruiting participants, sponsored by Emory University.

RECRUITING
Registry status
NA
Development phase
50 participants
Enrollment target

Study Summary

PTSD is one of the most universal and severe psychiatric disorders whose incidence continues to rise due to the common exposure to severe trauma in the United States and worldwide. After trauma, a proportion of individuals maintains high symptoms of PTSD and depression, which can persist for years. The early weeks following trauma present a unique opportunity to deliver early interventions that can prevent chronic PTSD and depression from occurring, and the researchers propose a brain-based intervention that will reduce reactivity to threat, an early risk mechanism for chronic PTSD. This study is being done to learn more about whether brain stimulation in the weeks after a trauma can change brain activity that is linked to Post-Traumatic Stress Disorder (PTSD).

Primary Outcome

Amygdala reactivity during fear processing will be assessed by fMRI responses as participants viewed 15 blocks each of fearful face and neutral face stimuli, while amygdala reactivity was measured. The amygdala will be separated into the right and left hemispheres. The right amygdala is the primary outcome measure. fMRI measures the blood oxygen level-dependent response, a measure of how much more oxygenated blood there is in a certain brain region, which reflects activation of the brain region

Interventions

  • DEVICE Transcranial Magnetic Stimulation (TMS)
  • OTHER TMS Sham

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2026-06-18
Est. Completion 2028-03
Phase NA
Emory University

1,208 total trials

What NCT07568145 shows while recruiting

NCT07568145 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which Transcranial Magnetic Stimulation (TMS) is the first listed.

NCT07568145 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07568145 about?

NCT07568145 is a clinical study titled "The PREVENT Resilience Study". PTSD is one of the most universal and severe psychiatric disorders whose incidence continues to rise due to the common exposure to severe trauma in the United States and worldwide. After trauma, a proportion of individuals maintains high symptoms of PTSD and depression, which can persist for years. ...

What is the current status of trial NCT07568145?

This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2026-06-18. Estimated completion is 2028-03.

What interventions are being tested in trial NCT07568145?

The interventions under investigation include: Transcranial Magnetic Stimulation (TMS) (DEVICE), TMS Sham (OTHER).

Who is sponsoring clinical trial NCT07568145?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07568145's enrollment target sits among peer trials

50 1279th of 2000 higher than 622 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07568145, the US trial registry maintained by the National Library of Medicine. NCT07568145 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.