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NCT07562451 · ClinicalTrials.gov registry record · NA

Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing

A NA study, sponsored by Emory University.

Not yet
Registry status
NA
Development phase
25
Enrollment target

NCT07562451: Clinical Trial NA study, sponsored by Emory University.

NCT07562451 is a NA study that has not yet begun recruiting, run by Emory University. The registered enrollment target is 25 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07562451, a NA study, has not yet begun recruiting, sponsored by Emory University.

NOT YET RECRUITING
Registry status
NA
Development phase
25 participants
Enrollment target

Study Summary

The goal of this clinical trial is to evaluate whether a 4-week music therapy (MT) intervention can reduce chronic pain and improve psychosocial outcomes in youth with sickle cell disease (SCD). The main questions it aims to answer are: * Does MT reduce pain intensity, frequency of pain episodes, and improve health-related quality of life (HRQoL)? * Does MT alter immune cell composition and gene expression in inflammatory pathways, as measured by single-cell RNA sequencing (scRNA-seq)? Researchers will compare participants randomized to music therapy versus a control condition to see if MT produces superior improvements in pain and psychosocial outcomes, and distinct molecular changes.

Primary Outcome

The Brief Pain Inventory (BPI) is a validated self-report questionnaire that measures both the severity of pain and the degree to which pain interferes with daily activities. Pain intensity is rated on a 0-10 numeric scale (0 = no pain, 10 = worst pain imaginable). Pain interference items are also scored 0-10 (0 = does not interfere, 10 = completely interferes). Greater scores indicate more severe pain and greater interference with daily activities.

Interventions

  • OTHER Standard of Care
  • OTHER Music Therapy

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2026-07
Est. Completion 2028-04
Phase NA
Emory University

1,208 total trials

What is known before NCT07562451 opens enrollment

NCT07562451 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 2 interventions - of which Standard of Care is the first listed.

NCT07562451 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07562451 about?

NCT07562451 is a clinical study titled "Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing". The goal of this clinical trial is to evaluate whether a 4-week music therapy (MT) intervention can reduce chronic pain and improve psychosocial outcomes in youth with sickle cell disease (SCD). The main questions it aims to answer are: * Does MT reduce pain intensity, frequency of pain episodes, ...

What is the current status of trial NCT07562451?

This trial is currently not yet recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2026-07. Estimated completion is 2028-04.

What interventions are being tested in trial NCT07562451?

The interventions under investigation include: Standard of Care (OTHER), Music Therapy (OTHER).

Who is sponsoring clinical trial NCT07562451?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07562451's enrollment target sits among peer trials

25 1712th of 2000 higher than 265 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07562451, the US trial registry maintained by the National Library of Medicine. NCT07562451 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.