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NCT07558122 · ClinicalTrials.gov registry record · Phase 1
Malaria CVD 36000; Gates INV090205
A Phase 1 study, sponsored by University of Maryland, Baltimore.
- Not yet
- Registry status
- Phase 1
- Development phase
- 32
- Enrollment target
NCT07558122 is a Phase 1 study that has not yet begun recruiting, run by University of Maryland, Baltimore. The registered enrollment target is 32 participants.
The verdict
NCT07558122, a Phase 1 study, has not yet begun recruiting, sponsored by University of Maryland, Baltimore.
- NOT YET RECRUITING
- Registry status
- Phase 1
- Development phase
- 32 participants
- Enrollment target
Study Summary
In order to control infections, the investigators must first detect them. Biosensor devices may allow early detection and intervention for infectious diseases, helping the investigators to recognize infections early, and allow for early treatment. This will lower transmission of infections and lower costs for treating someone who becomes ill. This is a study testing whether a wearable device such as a wristband and/or earphones can measure early biologic signals to detect identify infection in prior to seeing symptoms related of a disease. As a first test of this technology, the investigators will expose participants to injectable malaria or placebo. This is called a "Controlled Human Malaria Infection" (CHMI). Everyone who takes part in the CHMI may get malaria infection. The investigators will detect malaria using standard blood tests. The investigators will also look for early symptoms of malaria infection like changes in temperature, heart rate, breathing, sleep patterns, and changes in skin and muscle activity or voice. These signals may allow the investigators to detect early malaria infection. This is a study testing whether a wearable device such as a wristband and/or earphones can measure early biologic signals to detect malaria infection before symptoms occur, as confirmed by standard blood testing.
Interventions
- OTHER Placebo
- BIOLOGICAL PfSPZ Challenge (NF54)
- DEVICE Wearable Biosensor Devices
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2026-06-13 |
| Est. Completion | 2026-08 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07558122
The ClinicalTrials.gov registry entry for NCT07558122 describes a study currently listed as not yet recruiting, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT07558122 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07558122 about?
NCT07558122 is a clinical study titled "Malaria CVD 36000; Gates INV090205". In order to control infections, the investigators must first detect them. Biosensor devices may allow early detection and intervention for infectious diseases, helping the investigators to recognize infections early, and allow for early treatment. This will lower transmission of infections and lower...
What is the current status of trial NCT07558122?
This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2026-06-13. Estimated completion is 2026-08.
What interventions are being tested in trial NCT07558122?
The interventions under investigation include: Placebo (OTHER), PfSPZ Challenge (NF54) (BIOLOGICAL), Wearable Biosensor Devices (DEVICE).
Who is sponsoring clinical trial NCT07558122?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
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