Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07552766 · ClinicalTrials.gov registry record · Phase 4
A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements
A Phase 4 study, sponsored by Nemours Children's Clinic.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 90
- Enrollment target
NCT07552766 is a Phase 4 study that is actively recruiting participants, run by Nemours Children's Clinic. The registered enrollment target is 90 participants.
The verdict
NCT07552766, a Phase 4 study, is actively recruiting participants, sponsored by Nemours Children's Clinic.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 90 participants
- Enrollment target
Study Summary
This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children undergoing surgical fixation of upper extremity long bone fractures under general anesthesia. Ninety pediatric patients, ages 3-18 will be enrolled and randomized 1:1 to receive either IV lidocaine or placebo (normal saline) during surgery. All participants will receive standardized anesthesia care and postoperative pain management. Opioid consumption and pain scores will be measured intraoperatively and throughout the postoperative recovery, with the primary outcome focused on total opioid use 60 minutes after arrival to the post-anesthesia care unit (PACU). Secondary outcomes include opioid use at additional time points, postoperative pain scores, PACU length of stay, rescue antiemetic use and the relationship between infusion duration and outcomes. Patients will be closely monitored for signs of local anesthetic systemic toxicity and other adverse events. The goal of this study is to determine whether IV lidocaine is an effective opioid-sparing adjunct in pediatric orthopedic surgery and to support safer, multimodal analgesia strategies.
Interventions
- OTHER Standard of Care (SOC)
- DRUG Lidocaine Infusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2026-06-24 |
| Est. Completion | 2029-07 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07552766
The ClinicalTrials.gov registry entry for NCT07552766 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nemours Children's Clinic, which has 108 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Standard of Care (SOC) is the first listed.
NCT07552766 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07552766 about?
NCT07552766 is a clinical study titled "A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements". This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children undergoing surgical fixation of upper extremity long bone fractures under gener...
What is the current status of trial NCT07552766?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 90 participants. The study started on 2026-06-24. Estimated completion is 2029-07.
What interventions are being tested in trial NCT07552766?
The interventions under investigation include: Standard of Care (SOC) (OTHER), Lidocaine Infusion (DRUG).
Who is sponsoring clinical trial NCT07552766?
This trial is sponsored by Nemours Children's Clinic, which has 108 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.