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NCT07548164 · ClinicalTrials.gov registry record · Phase 3
Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer
A Phase 3 study, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 224
- Enrollment target
NCT07548164: Recruiting Phase 3 study, sponsored by Memorial Sloan Kettering Cancer Center.
NCT07548164 is a Phase 3 study that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 224 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07548164, a Phase 3 study, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 224 participants
- Enrollment target
Study Summary
In this study the investigators will find out whether the use of a new type of boost approach called irreversible electroporation (IRE) is as effective as the standard boost approach of radiation therapy for participants with intermediate-risk prostate cancer receiving standard stereotactic body radiotherapy (SBRT).
Primary Outcome
The primary objective is to demonstrate that Irreversible Electroporation/IRE boost is non-inferior with respect to negative biopsy rate at 2 years compared to Radiation Therapy/RT boost. This is measured by the two-year biopsy negative rate for the control group and the intervention group.
Interventions
- RADIATION Stereotactic Body Radiation Therapy
- DEVICE NanoKnife System
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 224 participants |
| Start Date | 2026-04-16 |
| Est. Completion | 2029-04-16 |
| Phase | Phase 3 |
What NCT07548164 shows while recruiting
NCT07548164 is an interventional study that assigns participants to a tested intervention. The registered 224 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (71% lower).
The record links to 0 conditions, and to 2 interventions - of which Stereotactic Body Radiation Therapy is the first listed.
NCT07548164 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07548164 about?
NCT07548164 is a clinical study titled "Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer". In this study the investigators will find out whether the use of a new type of boost approach called irreversible electroporation (IRE) is as effective as the standard boost approach of radiation therapy for participants with intermediate-risk prostate cancer receiving standard stereotactic body rad...
What is the current status of trial NCT07548164?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 224 participants. The study started on 2026-04-16. Estimated completion is 2029-04-16.
What interventions are being tested in trial NCT07548164?
The interventions under investigation include: Stereotactic Body Radiation Therapy (RADIATION), NanoKnife System (DEVICE).
Who is sponsoring clinical trial NCT07548164?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07548164's enrollment target sits among peer trials
224 1317th of 2000 higher than 684 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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