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NCT07544251 · ClinicalTrials.gov registry record · Phase 4
Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.
A Phase 4 study, sponsored by Integrative Skin Science and Research.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 30
- Enrollment target
NCT07544251: Recruiting Phase 4 study, sponsored by Integrative Skin Science and Research.
NCT07544251 is a Phase 4 study that is actively recruiting participants, run by Integrative Skin Science and Research. The registered enrollment target is 30 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07544251, a Phase 4 study, is actively recruiting participants, sponsored by Integrative Skin Science and Research.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 30 participants
- Enrollment target
Study Summary
This study is being done to help better understand how the gut and skin bacteria of the body change when people with acne are treated with Sarecycline or Doxycycline. The bacteria in the gut and on the skin will be studied to see how each treatment may affect them and whether they change the profile of the bacteria that is present.
Primary Outcome
Assessing change in the relative abundance of tetracycline resistant bacteria in the gut microbiome following treatment.
Interventions
- DRUG Doxycycline
- DRUG Sarecycline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2026-04-20 |
| Est. Completion | 2027-06 |
| Phase | Phase 4 |
What NCT07544251 shows while recruiting
NCT07544251 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which Doxycycline is the first listed.
NCT07544251 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07544251 about?
NCT07544251 is a clinical study titled "Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.". This study is being done to help better understand how the gut and skin bacteria of the body change when people with acne are treated with Sarecycline or Doxycycline. The bacteria in the gut and on the skin will be studied to see how each treatment may affect them and whether they change the profile...
What is the current status of trial NCT07544251?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2026-04-20. Estimated completion is 2027-06.
What interventions are being tested in trial NCT07544251?
The interventions under investigation include: Doxycycline (DRUG), Sarecycline (DRUG).
Who is sponsoring clinical trial NCT07544251?
This trial is sponsored by Integrative Skin Science and Research, which has 15 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07544251's enrollment target sits among peer trials
30 1552nd of 2000 higher than 367 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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