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NCT07542873 · ClinicalTrials.gov registry record · NA
Iron Absorption in The Low Oxygen Exposure and Weight Status (LOWS) Study
A NA study, sponsored by Pennington Biomedical Research Center.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT07542873: Recruiting NA study, sponsored by Pennington Biomedical Research Center.
NCT07542873 is a NA study that is actively recruiting participants, run by Pennington Biomedical Research Center. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07542873, a NA study, is actively recruiting participants, sponsored by Pennington Biomedical Research Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
Declines in iron status are common in those with obesity and may be due to obesity-related chronic inflammation; however, the effects of reducing inflammation following diet-induced weight loss on iron metabolism are poorly understood. Low environmental oxygen exposure increases dietary iron absorption and availability to supply iron for erythropoiesis but has not yet been tested in the context of weight loss. This study is designed to investigate diet-induced weight loss (inflammation reduction) and overnight low oxygen exposure (erythropoiesis stimulating agent) as strategies to improve dietary iron absorption in obesity.
Primary Outcome
Fractional iron absorption will be measured during the baseline weight maintenance phase (day -7) and at the end of the study (day 42). Change in fractional iron absorption will be calculated as: fractional iron absorption on day 42 - fractional iron absorption on day -7.
Interventions
- OTHER Normobaric hypoxia (NH)
- OTHER Normobaric normoxia (NN)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-04-21 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT07542873 shows while recruiting
NCT07542873 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Normobaric hypoxia (NH) is the first listed.
NCT07542873 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07542873 about?
NCT07542873 is a clinical study titled "Iron Absorption in The Low Oxygen Exposure and Weight Status (LOWS) Study". Declines in iron status are common in those with obesity and may be due to obesity-related chronic inflammation; however, the effects of reducing inflammation following diet-induced weight loss on iron metabolism are poorly understood. Low environmental oxygen exposure increases dietary iron absorpt...
What is the current status of trial NCT07542873?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-04-21. Estimated completion is 2026-06-30.
What interventions are being tested in trial NCT07542873?
The interventions under investigation include: Normobaric hypoxia (NH) (OTHER), Normobaric normoxia (NN) (OTHER).
Who is sponsoring clinical trial NCT07542873?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07542873's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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