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NCT07539025 · ClinicalTrials.gov registry record · NA
Cervical Spinal Cord Associative Plasticity
A NA study, sponsored by Columbia University.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT07539025 is a NA study that is actively recruiting participants, run by Columbia University. The registered enrollment target is 20 participants.
The verdict
NCT07539025, a NA study, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
Associative plasticity has been used to promote functional recovery from conditions affecting movement. Prior work from the Carmel laboratory has shown that paired associative stimulation protocols timed to converge in the cervical spinal cord induce significantly larger upper limb motor responses than if timed to converge in the motor cortex. The goal of this prospective experimental study in typically developing adults is to test the effects of pairing sub-threshold hand motor cortical and median nerve stimulation targeted to induce plasticity in the cervical spinal cord, rather than in the motor cortex. Based on preliminary data, the investigators are performing a confirmatory study to test the physiological and behavioral effects of the paired brain and peripheral nerve protocol, called the SCAP-Nerve protocol. This study will first be conducted in typically developing adults to confirm the cervical spinal cord as the ideal target and verify the present stimulation parameters are sufficient to promote induction of associative plasticity of sensorimotor connections for manual dexterity. The outcomes from this study could then be translated to efficacy studies in people with spinal cord injury and cerebral palsy to promote clinically meaningful improvements in dexterity.
Interventions
- OTHER SCAP
- DEVICE MagPro X100
- DEVICE Digitimer DS8R
- OTHER Paired non-associative stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-05-09 |
| Est. Completion | 2029-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07539025
The ClinicalTrials.gov registry entry for NCT07539025 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which SCAP is the first listed.
NCT07539025 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07539025 about?
NCT07539025 is a clinical study titled "Cervical Spinal Cord Associative Plasticity". Associative plasticity has been used to promote functional recovery from conditions affecting movement. Prior work from the Carmel laboratory has shown that paired associative stimulation protocols timed to converge in the cervical spinal cord induce significantly larger upper limb motor responses t...
What is the current status of trial NCT07539025?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-05-09. Estimated completion is 2029-06.
What interventions are being tested in trial NCT07539025?
The interventions under investigation include: SCAP (OTHER), MagPro X100 (DEVICE), Digitimer DS8R (DEVICE), Paired non-associative stimulation (OTHER).
Who is sponsoring clinical trial NCT07539025?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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