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NCT07538336 · ClinicalTrials.gov registry record · Phase 2

Targeting Interferon Gamma With Emapalumab to Lung Transplant Recipients With Interferon Gamma-high Acute Lung Allograft Dysfunction

A Phase 2 study, sponsored by University of California, San Francisco.

Not yet
Registry status
Phase 2
Development phase
40
Enrollment target

NCT07538336 is a Phase 2 study that has not yet begun recruiting, run by University of California, San Francisco. The registered enrollment target is 40 participants.

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The verdict

NCT07538336, a Phase 2 study, has not yet begun recruiting, sponsored by University of California, San Francisco.

NOT YET RECRUITING
Registry status
Phase 2
Development phase
40 participants
Enrollment target

Study Summary

This study is testing a medication called emapalumab to see if it can help people who have had a lung transplant and are experiencing a sudden drop in lung function, called acute lung allograft dysfunction (ALAD). ALAD is a serious condition that can happen after a lung transplant and can lead to worsening breathing and other complications. Right now, there is no approved treatment for ALAD. The main goal is to see if lung function improves, meaning it returns close to your usual (baseline) level within 90 days.

Interventions

  • DRUG Placebo
  • DRUG Emapalumab

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2026-11-02
Est. Completion 2028-11-01
Phase Phase 2

What the Registry Record Tells You About NCT07538336

The ClinicalTrials.gov registry entry for NCT07538336 describes a study currently listed as not yet recruiting, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT07538336 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07538336 about?

NCT07538336 is a clinical study titled "Targeting Interferon Gamma With Emapalumab to Lung Transplant Recipients With Interferon Gamma-high Acute Lung Allograft Dysfunction". This study is testing a medication called emapalumab to see if it can help people who have had a lung transplant and are experiencing a sudden drop in lung function, called acute lung allograft dysfunction (ALAD). ALAD is a serious condition that can happen after a lung transplant and can lead to w...

What is the current status of trial NCT07538336?

This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2026-11-02. Estimated completion is 2028-11-01.

What interventions are being tested in trial NCT07538336?

The interventions under investigation include: Placebo (DRUG), Emapalumab (DRUG).

Who is sponsoring clinical trial NCT07538336?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.