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NCT07537413 · ClinicalTrials.gov registry record · Phase 4

Ceftriaxone Dosage for Non-Critical Community-Acquired Pneumonia

A Phase 4 study, sponsored by University of Maryland, Baltimore.

Not yet
Registry status
Phase 4
Development phase
430
Enrollment target

NCT07537413: Clinical Trial Phase 4 study, sponsored by University of Maryland, Baltimore.

NCT07537413 is a Phase 4 study that has not yet begun recruiting, run by University of Maryland, Baltimore. The registered enrollment target is 430 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07537413, a Phase 4 study, has not yet begun recruiting, sponsored by University of Maryland, Baltimore.

NOT YET RECRUITING
Registry status
Phase 4
Development phase
430 participants
Enrollment target

Study Summary

Aim: Demonstrate the equivalent efficacy and superior safety of Ceftriaxone 1 gram daily compared with Ceftriaxone 2 grams daily among hospitalized patients with community-acquired pneumonia who are not admitted to the intensive care unit.\<p\> Hypothesis: Among hospitalized patients outside of the intensive care unit with community-acquired pneumonia who are prescribed Ceftriaxone, a dosage of 1 gram daily will be associated with an equivalent rate of clinical cure and fewer adverse events than a dosage of 2 grams daily.

Primary Outcome

Defined by discharge from the hospital or antibiotic treatment for \< 8 days without any of the following: requirement for antibiotic escalation, admission to an intensive care unit, mechanical or noninvasive ventilation, readmission within 30 days, or mortality within 30 days

Interventions

  • DRUG Ceftriaxone 1 gram daily
  • DRUG Ceftriaxone 2 grams daily

Trial Details

FieldValue
Enrollment Target 430 participants
Start Date 2026-09-01
Est. Completion 2028-02-28
Phase Phase 4
University of Maryland, Baltimore

560 total trials

What is known before NCT07537413 opens enrollment

NCT07537413 is an interventional study that assigns participants to a tested intervention. The registered 430 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (17% lower).

The record links to 0 conditions, and to 2 interventions - of which Ceftriaxone 1 gram daily is the first listed.

NCT07537413 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07537413 about?

NCT07537413 is a clinical study titled "Ceftriaxone Dosage for Non-Critical Community-Acquired Pneumonia". Aim: Demonstrate the equivalent efficacy and superior safety of Ceftriaxone 1 gram daily compared with Ceftriaxone 2 grams daily among hospitalized patients with community-acquired pneumonia who are not admitted to the intensive care unit.\<p\> Hypothesis: Among hospitalized patients outside of the...

What is the current status of trial NCT07537413?

This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 430 participants. The study started on 2026-09-01. Estimated completion is 2028-02-28.

What interventions are being tested in trial NCT07537413?

The interventions under investigation include: Ceftriaxone 1 gram daily (DRUG), Ceftriaxone 2 grams daily (DRUG).

Who is sponsoring clinical trial NCT07537413?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07537413's enrollment target sits among peer trials

430 194th of 2000 higher than 1,806 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07537413, the US trial registry maintained by the National Library of Medicine. NCT07537413 (mid enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.