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NCT07535008 · ClinicalTrials.gov registry record · NA
Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease
A NA study, sponsored by Fred Hutchinson Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 45
- Enrollment target
NCT07535008: Recruiting NA study, sponsored by Fred Hutchinson Cancer Center.
NCT07535008 is a NA study that is actively recruiting participants, run by Fred Hutchinson Cancer Center. The registered enrollment target is 45 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07535008, a NA study, is actively recruiting participants, sponsored by Fred Hutchinson Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 45 participants
- Enrollment target
Study Summary
This clinical trial evaluates the feasibility and effectiveness of a post-transplant dental cleaning for the prevention of chronic graft versus host disease (GVHD) in patients undergoing an allogeneic hematopoietic cell transplant (HCT). HCT is the only curative treatment for some types of blood cancer. Unfortunately, this approach can lead to the development of GVHD, which is a disease caused when cells from a donated stem cell graft attack the normal tissue of the transplant patient. Some research has shown that the bacteria that is present in the dental plaque soon after transplant may affect the development of chronic GVHD. Dental cleanings prior to transplant are part of the normal standard of care for patients undergoing HCT. Adding an additional cleaning shortly after HCT may be effective for preventing the development of chronic GVHD.
Interventions
- PROCEDURE Dental Cleaning
- PROCEDURE Dental Plaque sampling
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2026-07-15 |
| Est. Completion | 2029-04-30 |
| Phase | NA |
What NCT07535008 shows while recruiting
NCT07535008 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Dental Cleaning is the first listed.
NCT07535008 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07535008 about?
NCT07535008 is a clinical study titled "Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease". This clinical trial evaluates the feasibility and effectiveness of a post-transplant dental cleaning for the prevention of chronic graft versus host disease (GVHD) in patients undergoing an allogeneic hematopoietic cell transplant (HCT). HCT is the only curative treatment for some types of blood can...
What is the current status of trial NCT07535008?
This trial is currently recruiting. It is a NA study. The enrollment target is 45 participants. The study started on 2026-07-15. Estimated completion is 2029-04-30.
What interventions are being tested in trial NCT07535008?
The interventions under investigation include: Dental Cleaning (PROCEDURE), Dental Plaque sampling (PROCEDURE).
Who is sponsoring clinical trial NCT07535008?
This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07535008's enrollment target sits among peer trials
45 1411th of 2000 higher than 578 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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