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NCT07534722 · ClinicalTrials.gov registry record · NA
Transcutaneous Auricular Vagus Nerve Stimulation for Attenuation of Inflammatory Response and Blood Pressure in Type B Aortic Dissection
A NA study, sponsored by Washington University School of Medicine.
- Not yet
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT07534722 is a NA study that has not yet begun recruiting, run by Washington University School of Medicine. The registered enrollment target is 60 participants.
The verdict
NCT07534722, a NA study, has not yet begun recruiting, sponsored by Washington University School of Medicine.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
Patients with uncomplicated Type B aortic dissections (TBAD) are traditionally treated in the ICU for impulse control, with BP and HR goals. Local and systemic inflammation often is a resulting consequence of acute aortic dissection. Vagus nerve stimulation can impact hemodynamics and inflammation. This study will utilize a novel transcutaneous auricular vagus nerve stimulator (taVNS) as part of the treatment for patients with TBAD. It's hypothesized that vagus nerve stimulation may provide benefit to the acute TBAD population admitted to ICU by two distinct mechanisms: 1. Through upregulation of parasympathetic pathways which may augment chemical heart rate and blood pressure control through bioelectric stimulation, and 2. downregulation of inflammatory pathways through a neuro-immunological axis.
Interventions
- DEVICE Auricular Vagus Nerve Stimulator
- DEVICE 3D Printed Earpiece
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2026-04-17 |
| Est. Completion | 2027-04-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07534722
The ClinicalTrials.gov registry entry for NCT07534722 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Auricular Vagus Nerve Stimulator is the first listed.
NCT07534722 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07534722 about?
NCT07534722 is a clinical study titled "Transcutaneous Auricular Vagus Nerve Stimulation for Attenuation of Inflammatory Response and Blood Pressure in Type B Aortic Dissection". Patients with uncomplicated Type B aortic dissections (TBAD) are traditionally treated in the ICU for impulse control, with BP and HR goals. Local and systemic inflammation often is a resulting consequence of acute aortic dissection. Vagus nerve stimulation can impact hemodynamics and inflammation. ...
What is the current status of trial NCT07534722?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2026-04-17. Estimated completion is 2027-04-01.
What interventions are being tested in trial NCT07534722?
The interventions under investigation include: Auricular Vagus Nerve Stimulator (DEVICE), 3D Printed Earpiece (DEVICE).
Who is sponsoring clinical trial NCT07534722?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
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