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NCT07531901 · ClinicalTrials.gov registry record · NA
Evaluating the Feasibility and Reliability of Using Handheld Nebulizers to Conduct Cough Sensitivity Testing With Citric Acid
A NA study, sponsored by University of Montana.
- Recruiting
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT07531901: Recruiting NA study, sponsored by University of Montana.
NCT07531901 is a NA study that is actively recruiting participants, run by University of Montana. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07531901, a NA study, is actively recruiting participants, sponsored by University of Montana.
- RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
Objective cough reflex sensitivity testing is typically restricted to specialized research laboratories due to reliance on expensive dosimeter-controlled aerosol delivery systems. This study evaluates the feasibility and reliability of a low-cost alternative method using a handheld nebulizer for citric acid cough challenge testing. Healthy adult participants will complete cough reflex sensitivity testing using both a standard dosimeter-controlled nebulizer system (Cosmed QuarkSpiro) and a handheld nebulizer (DeVilbiss 45). The study will compare cough threshold outcomes between methods to determine whether handheld nebulizer-based testing produces comparable and reproducible measurements.
Primary Outcome
The test-retest reliability (Intraclass correlation coefficient) of the citric acid concentration required to elicit two coughs during cough challenge testing will be evaluated and compared for each testing method.
Interventions
- DEVICE Cosmed QuarkSpiro Dosimeter-Controlled Nebulizer
- DEVICE DeVilbiss 45 Handheld Nebulizer
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2026-06-05 |
| Est. Completion | 2027-02-28 |
| Phase | NA |
What NCT07531901 shows while recruiting
NCT07531901 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Cosmed QuarkSpiro Dosimeter-Controlled Nebulizer is the first listed.
NCT07531901 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07531901 about?
NCT07531901 is a clinical study titled "Evaluating the Feasibility and Reliability of Using Handheld Nebulizers to Conduct Cough Sensitivity Testing With Citric Acid". Objective cough reflex sensitivity testing is typically restricted to specialized research laboratories due to reliance on expensive dosimeter-controlled aerosol delivery systems. This study evaluates the feasibility and reliability of a low-cost alternative method using a handheld nebulizer for cit...
What is the current status of trial NCT07531901?
This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2026-06-05. Estimated completion is 2027-02-28.
What interventions are being tested in trial NCT07531901?
The interventions under investigation include: Cosmed QuarkSpiro Dosimeter-Controlled Nebulizer (DEVICE), DeVilbiss 45 Handheld Nebulizer (DEVICE).
Who is sponsoring clinical trial NCT07531901?
This trial is sponsored by University of Montana, which has 24 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07531901's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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