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NCT07520292 · ClinicalTrials.gov registry record · Phase 1
Study of NTX-2001 on Alcohol Consumption in Alcohol Use Disorder
A Phase 1 study, sponsored by Newleos Therapeutics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 50
- Enrollment target
NCT07520292: Recruiting Phase 1 study, sponsored by Newleos Therapeutics.
NCT07520292 is a Phase 1 study that is actively recruiting participants, run by Newleos Therapeutics. The registered enrollment target is 50 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07520292, a Phase 1 study, is actively recruiting participants, sponsored by Newleos Therapeutics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 50 participants
- Enrollment target
Study Summary
The primary goal of this Phase 1b clinical trial is to evaluate the effects of a novel TAAR1 receptor partial agonist (NTX-2001) in adults with Alcohol Use Disorder (AUD). The main questions this trial aims to answer are: * Does NTX-2001 affect alcohol consumption in adults with AUD? * Is NTX-2001 safe and well tolerated in adults with AUD? Researchers will compare the effects of NTX-2001 with matching placebo (look-alike capsule that contains no drug). Participants will: * Take NTX-2001 or matching placebo every day for 2 weeks * Visit the clinic 4 times over the course of 10 weeks
Interventions
- DRUG Placebo
- DRUG NTX-2001
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2026-03-20 |
| Est. Completion | 2027-03 |
| Phase | Phase 1 |
What NCT07520292 shows while recruiting
NCT07520292 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT07520292 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07520292 about?
NCT07520292 is a clinical study titled "Study of NTX-2001 on Alcohol Consumption in Alcohol Use Disorder". The primary goal of this Phase 1b clinical trial is to evaluate the effects of a novel TAAR1 receptor partial agonist (NTX-2001) in adults with Alcohol Use Disorder (AUD). The main questions this trial aims to answer are: * Does NTX-2001 affect alcohol consumption in adults with AUD? * Is NTX-2001 ...
What is the current status of trial NCT07520292?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2026-03-20. Estimated completion is 2027-03.
What interventions are being tested in trial NCT07520292?
The interventions under investigation include: Placebo (DRUG), NTX-2001 (DRUG).
Who is sponsoring clinical trial NCT07520292?
This trial is sponsored by Newleos Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07520292's enrollment target sits among peer trials
50 973rd of 2000 higher than 984 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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