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NCT07517172 · ClinicalTrials.gov registry record · NA
Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study
A NA study, sponsored by University of Minnesota.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT07517172: Recruiting NA study, sponsored by University of Minnesota.
NCT07517172 is a NA study that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07517172, a NA study, is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
This study is a randomized, double-blind, sham-controlled feasibility trial designed to assess the acceptability and preliminary efficacy of Transcutaneous Auricular Neurostimulation (tAN) for individuals with Temporomandibular Disorders (TMD). Approximately 40 participants will be enrolled to evaluate whether daily, home-based tAN sessions-which deliver mild electrical pulses to the auricular branch of the vagus nerve-can effectively reduce chronic orofacial pain and improve associated cognitive and psychosocial dysfunctions. The study monitors feasibility through retention and adherence rates while tracking secondary outcomes such as pain intensity, cognitive flexibility, and mood changes using validated scales and wearable smartwatch data . Ultimately, this research aims to generate the critical data necessary to inform larger clinical trials and potentially offer a non-pharmacological, non-invasive treatment option for patients refractory to traditional TMD therapies.
Primary Outcome
The proportion of enrolled participants who complete both baseline and post-treatment assessments. A retention rate of ≥50% is considered feasible.
Interventions
- DEVICE Sham Stimulation
- DEVICE Transcutaneous Auricular Neurostimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-05-20 |
| Est. Completion | 2027-09-30 |
| Phase | NA |
What NCT07517172 shows while recruiting
NCT07517172 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham Stimulation is the first listed.
NCT07517172 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07517172 about?
NCT07517172 is a clinical study titled "Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study". This study is a randomized, double-blind, sham-controlled feasibility trial designed to assess the acceptability and preliminary efficacy of Transcutaneous Auricular Neurostimulation (tAN) for individuals with Temporomandibular Disorders (TMD). Approximately 40 participants will be enrolled to evalu...
What is the current status of trial NCT07517172?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2026-05-20. Estimated completion is 2027-09-30.
What interventions are being tested in trial NCT07517172?
The interventions under investigation include: Sham Stimulation (DEVICE), Transcutaneous Auricular Neurostimulation (DEVICE).
Who is sponsoring clinical trial NCT07517172?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07517172's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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