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NCT07516964 · ClinicalTrials.gov registry record · NA
SLIT ABS: Study on Patients With Autoimmune Podocytopathy
A NA study, sponsored by Meyer Children's Hospital IRCCS.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT07516964 is a NA study that is actively recruiting participants, run by Meyer Children's Hospital IRCCS. The registered enrollment target is 50 participants.
The verdict
NCT07516964, a NA study, is actively recruiting participants, sponsored by Meyer Children's Hospital IRCCS.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
Nephrotic syndrome is a kidney condition that mainly affects children and is characterized by high levels of protein in the urine, low levels of protein in the blood, and swelling. While many children respond well to steroid treatment, a large proportion experience relapses or become dependent on therapy. In some cases, the disease does not respond to standard treatments and may progress to chronic kidney disease. Recent research suggests that, in addition to genetic factors, immune system mechanisms may play a key role in the development and progression of nephrotic syndrome. In particular, some patients produce autoantibodies against nephrin, an essential protein of the kidney filtration barrier. These autoantibodies may be associated with disease activity and treatment response. The aim of this study is to investigate the presence of anti-nephrin autoantibodies in children with nephrotic syndrome and to better understand their role in disease mechanisms and clinical outcomes.The study will also explore the presence of other autoantibodies targeting components of the glomerular filtration barrier. The study will use advanced laboratory techniques, including blood tests and detailed analysis of kidney biopsy samples, to identify these antibodies and their relationship with kidney structure and function. By integrating laboratory findings with clinical data, this study aims to improve the understanding of nephrotic syndrome and support the development of more personalized diagnostic and therapeutic strategies, with the goal of improving patient outcomes and reducing unnecessary or ineffective treatments.
Interventions
- OTHER Serum and renal tissue analysis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2025-06-10 |
| Est. Completion | 2036-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07516964
The ClinicalTrials.gov registry entry for NCT07516964 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Meyer Children's Hospital IRCCS, which has 6 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Serum and renal tissue analysis is the first listed.
NCT07516964 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07516964 about?
NCT07516964 is a clinical study titled "SLIT ABS: Study on Patients With Autoimmune Podocytopathy". Nephrotic syndrome is a kidney condition that mainly affects children and is characterized by high levels of protein in the urine, low levels of protein in the blood, and swelling. While many children respond well to steroid treatment, a large proportion experience relapses or become dependent on th...
What is the current status of trial NCT07516964?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2025-06-10. Estimated completion is 2036-10.
What interventions are being tested in trial NCT07516964?
The interventions under investigation include: Serum and renal tissue analysis (OTHER).
Who is sponsoring clinical trial NCT07516964?
This trial is sponsored by Meyer Children's Hospital IRCCS, which has 6 total clinical trials registered on ClinicalTrials.gov.
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