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NCT07515872 · ClinicalTrials.gov registry record · Phase 2

Long Duration High Frequency Ultrasound for the Treatment of Osteoarthritis

A Phase 2 study, sponsored by ZetrOZ.

Not yet
Registry status
Phase 2
Development phase
240
Enrollment target

NCT07515872: Clinical Trial Phase 2 study, sponsored by ZetrOZ.

NCT07515872 is a Phase 2 study that has not yet begun recruiting, run by ZetrOZ. The registered enrollment target is 240 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07515872, a Phase 2 study, has not yet begun recruiting, sponsored by ZetrOZ.

NOT YET RECRUITING
Registry status
Phase 2
Development phase
240 participants
Enrollment target

Study Summary

The purpose of this study is to assess the ability of long-duration high-frequency continuous-wave therapeutic ultrasound to alleviate knee Osteoarthritis pain over an 12-week period. The primary objective of this study is to evaluate the analgesic effect of ultrasound treatment in subjects suffering from knee Osteoarthritis pain. Secondary objectives are to assess the ability of ultrasound treatment to improve joint function.

Primary Outcome

Change in the self-described pain units on a scale by patient at baseline and post-treatment

Interventions

  • DEVICE Sustained Acoustic Device with 2.5% Diclofenac Patch
  • DEVICE Sustained Acoustic Device with 0% Diclofenac Patch
  • DRUG Intra articular injection

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2026-05-01
Est. Completion 2028-05-31
Phase Phase 2
ZetrOZ

17 total trials

What is known before NCT07515872 opens enrollment

NCT07515872 is an interventional study that assigns participants to a tested intervention. The registered 240 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% higher).

The record links to 0 conditions, and to 3 interventions - of which Sustained Acoustic Device with 2.5% Diclofenac Patch is the first listed.

NCT07515872 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07515872 about?

NCT07515872 is a clinical study titled "Long Duration High Frequency Ultrasound for the Treatment of Osteoarthritis". The purpose of this study is to assess the ability of long-duration high-frequency continuous-wave therapeutic ultrasound to alleviate knee Osteoarthritis pain over an 12-week period. The primary objective of this study is to evaluate the analgesic effect of ultrasound treatment in subjects sufferin...

What is the current status of trial NCT07515872?

This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2026-05-01. Estimated completion is 2028-05-31.

What interventions are being tested in trial NCT07515872?

The interventions under investigation include: Sustained Acoustic Device with 2.5% Diclofenac Patch (DEVICE), Sustained Acoustic Device with 0% Diclofenac Patch (DEVICE), Intra articular injection (DRUG).

Who is sponsoring clinical trial NCT07515872?

This trial is sponsored by ZetrOZ, which has 17 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07515872's enrollment target sits among peer trials

240 239th of 2000 higher than 1,746 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07515872, the US trial registry maintained by the National Library of Medicine. NCT07515872 (mid enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.