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NCT07513571 · ClinicalTrials.gov registry record · Phase 1

A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of AZD4954 and Vice Versa in Healthy Adults

A Phase 1 study, sponsored by AstraZeneca.

Recruiting
Registry status
Phase 1
Development phase
32
Enrollment target

NCT07513571: Recruiting Phase 1 study, sponsored by AstraZeneca.

NCT07513571 is a Phase 1 study that is actively recruiting participants, run by AstraZeneca. The registered enrollment target is 32 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07513571, a Phase 1 study, is actively recruiting participants, sponsored by AstraZeneca.

RECRUITING
Registry status
Phase 1
Development phase
32 participants
Enrollment target

Study Summary

The purpose this study is to measure the impact of laroprovstat (AZD0780) on the pharmacokinetics (PK) of AZD4954 and the impact of AZD4954 on the PK of laroprovstat in healthy male and female participants.

Primary Outcome

To assess the effect of a single dose of oral laroprovstat on the PK of a single dose of oral AZD4954 in healthy participants.

Interventions

  • DRUG AZD4954
  • DRUG Laroprovstat

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2026-04-10
Est. Completion 2026-07-09
Phase Phase 1
AstraZeneca

1,285 total trials

What NCT07513571 shows while recruiting

NCT07513571 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower).

The record links to 0 conditions, and to 2 interventions - of which AZD4954 is the first listed.

NCT07513571 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07513571 about?

NCT07513571 is a clinical study titled "A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of AZD4954 and Vice Versa in Healthy Adults". The purpose this study is to measure the impact of laroprovstat (AZD0780) on the pharmacokinetics (PK) of AZD4954 and the impact of AZD4954 on the PK of laroprovstat in healthy male and female participants.

What is the current status of trial NCT07513571?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2026-04-10. Estimated completion is 2026-07-09.

What interventions are being tested in trial NCT07513571?

The interventions under investigation include: AZD4954 (DRUG), Laroprovstat (DRUG).

Who is sponsoring clinical trial NCT07513571?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07513571's enrollment target sits among peer trials

32 1296th of 2000 higher than 679 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07513571, the US trial registry maintained by the National Library of Medicine. NCT07513571 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.