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NCT07510373 · ClinicalTrials.gov registry record · NA
Opioid Tapering After Hospital Discharge: Testing an Intervention to Improve Post-operative Opioid Prescribing
A NA study, sponsored by Montefiore Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 42
- Enrollment target
NCT07510373 is a NA study that is actively recruiting participants, run by Montefiore Medical Center. The registered enrollment target is 42 participants.
The verdict
NCT07510373, a NA study, is actively recruiting participants, sponsored by Montefiore Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 42 participants
- Enrollment target
Study Summary
The investigator team proposes a randomized clinical trial (RCT) to test a discharge opioid taper support ("DOTS") intervention that is embedded in the providers' workflow in the EHR to prompt them to prescribe an opioid taper for patients after orthopedic surgery that is tailored to patients' expected analgesic needs. DOTS includes: 1) a recommendation for a patient-specific opioid taper schedule based on opioid use prior to discharge, 2) an automated discharge opioid prescription based on the recommended taper schedule that providers can override, 3) a patient facing handout and 4) post-discharge telephonic support for patients. Providers will be randomly assigned 1:1 to 2 groups and who will each be assigned to DOTS ("DOTS providers") or TS ("TS providers") in a step-wedge design. EHR data will be extracted and telephone surveys of 100 patients over 12 weeks will be conducted after hospital discharge. The two specific aims are: 1. To determine the effectiveness of DOTS for reducing excessive opioid prescribing after orthopedic surgery. Hypothesis 1: Patients discharged by DOTS providers will be prescribed a lower initial mean morphine equivalent daily dose (MMED), fewer opioid pills, and over 12 weeks, will have fewer subsequent opioid prescriptions and incident long-term opioid therapy, compared to patients discharged by non-DOTS providers. Hypothesis 2. Age and frailty will be moderators; DOTS will be more effective at reducing excessive prescribing to older (65 years and older) and frailer patients. 2. To determine the positive and negative impact of DOTS on patient outcomes. Hypothesis 3: Compared to patients of non-DOTS providers, patients of DOTS providers will have improved pain and function, fewer adverse events, and less emergency post-operative care. Hypothesis 4: Age and frailty will be moderators; DOTS will be more effective at improving positive and reducing negative outcomes in older and frailer patients.
Interventions
- OTHER Treatment as Usual (TAU)
- OTHER Telephonic Support (TS) Providers
- OTHER DOTS Intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2026-04-12 |
| Est. Completion | 2028-04 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07510373
The ClinicalTrials.gov registry entry for NCT07510373 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Montefiore Medical Center, which has 345 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Treatment as Usual (TAU) is the first listed.
NCT07510373 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07510373 about?
NCT07510373 is a clinical study titled "Opioid Tapering After Hospital Discharge: Testing an Intervention to Improve Post-operative Opioid Prescribing". The investigator team proposes a randomized clinical trial (RCT) to test a discharge opioid taper support ("DOTS") intervention that is embedded in the providers' workflow in the EHR to prompt them to prescribe an opioid taper for patients after orthopedic surgery that is tailored to patients' expec...
What is the current status of trial NCT07510373?
This trial is currently recruiting. It is a NA study. The enrollment target is 42 participants. The study started on 2026-04-12. Estimated completion is 2028-04.
What interventions are being tested in trial NCT07510373?
The interventions under investigation include: Treatment as Usual (TAU) (OTHER), Telephonic Support (TS) Providers (OTHER), DOTS Intervention (OTHER).
Who is sponsoring clinical trial NCT07510373?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
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