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NCT07509008 · ClinicalTrials.gov registry record · Phase 1

Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum

A Phase 1 study, sponsored by M.D. Anderson Cancer Center.

Not yet
Registry status
Phase 1
Development phase
10
Enrollment target

NCT07509008: Clinical Trial Phase 1 study, sponsored by M.D. Anderson Cancer Center.

NCT07509008 is a Phase 1 study that has not yet begun recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 10 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07509008, a Phase 1 study, has not yet begun recruiting, sponsored by M.D. Anderson Cancer Center.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
10 participants
Enrollment target

Study Summary

The goal of this clinical research study is to study the recommended dose of TROP2 CAR/IL-15 TGFBR2 KO NK cells that can be given intraperitoneally (infused directly into the stomach area) to participants with adenocarcinoma of the stomach that has spread to the peritoneum. The safety and effectiveness of this treatment will also be studied.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Fludarabine
  • DRUG Rimiducid (AP1903)
  • DRUG TGFBR2 KO CAR27/IL-15 NK cells

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2026-09-01
Est. Completion 2030-07-01
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT07509008

The ClinicalTrials.gov registry entry for NCT07509008 describes a study currently listed as not yet recruiting, categorized as Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Cyclophosphamide is the first listed.

NCT07509008 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07509008 about?

NCT07509008 is a clinical study titled "Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum". The goal of this clinical research study is to study the recommended dose of TROP2 CAR/IL-15 TGFBR2 KO NK cells that can be given intraperitoneally (infused directly into the stomach area) to participants with adenocarcinoma of the stomach that has spread to the peritoneum. The safety and effectiven...

What is the current status of trial NCT07509008?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2026-09-01. Estimated completion is 2030-07-01.

What interventions are being tested in trial NCT07509008?

The interventions under investigation include: Cyclophosphamide (DRUG), Fludarabine (DRUG), Rimiducid (AP1903) (DRUG), TGFBR2 KO CAR27/IL-15 NK cells (DRUG).

Who is sponsoring clinical trial NCT07509008?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.