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NCT07508241 · ClinicalTrials.gov registry record · Phase 1
A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity
A Phase 1 study, sponsored by Pfizer.
- Active
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
NCT07508241: Active Phase 1 study, sponsored by Pfizer.
NCT07508241 is a Phase 1 study that is active but no longer recruiting, run by Pfizer. The registered enrollment target is 22 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07508241, a Phase 1 study, is active but no longer recruiting, sponsored by Pfizer.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
Study Summary
This study looks at how a study medicine called PF-08653944 affects how quickly the stomach empties food after eating. It is being done in adults who are overweight or have obesity. Participants will receive the study medicine for a short period, and doctors will measure how the medicine moves through the stomach and monitor safety. The goal is to better understand how this medicine works in the body and to check for any side effects. The information from this study may help researchers plan future studies of this medicine.
Primary Outcome
To assess the effect of multiple SC doses of PF-08653944 on the plasma PK profile of acetaminophen, a marker for gastric emptying, in healthy adult participants with overweight or obesity.
Interventions
- DRUG Acetaminophen
- DRUG PF-08653944
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2026-03-31 |
| Est. Completion | 2027-01-27 |
| Phase | Phase 1 |
What the registry record for NCT07508241 still lists
NCT07508241 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower).
The record links to 0 conditions, and to 2 interventions - of which Acetaminophen is the first listed.
NCT07508241 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07508241 about?
NCT07508241 is a clinical study titled "A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity". This study looks at how a study medicine called PF-08653944 affects how quickly the stomach empties food after eating. It is being done in adults who are overweight or have obesity. Participants will receive the study medicine for a short period, and doctors will measure how the medicine moves thro...
What is the current status of trial NCT07508241?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2026-03-31. Estimated completion is 2027-01-27.
What interventions are being tested in trial NCT07508241?
The interventions under investigation include: Acetaminophen (DRUG), PF-08653944 (DRUG).
Who is sponsoring clinical trial NCT07508241?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07508241's enrollment target sits among peer trials
22 1601st of 2000 higher than 386 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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