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NCT07501455 · ClinicalTrials.gov registry record · NA
Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis
A NA study, sponsored by Kenvue Brands.
- Recruiting
- Registry status
- NA
- Development phase
- 250
- Enrollment target
NCT07501455: Recruiting NA study, sponsored by Kenvue Brands.
NCT07501455 is a NA study that is actively recruiting participants, run by Kenvue Brands. The registered enrollment target is 250 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07501455, a NA study, is actively recruiting participants, sponsored by Kenvue Brands.
- RECRUITING
- Registry status
- NA
- Development phase
- 250 participants
- Enrollment target
Study Summary
This study is a six-week, double-blind, randomized, parallel-group controlled clinical study. The objective of this study is to evaluate the changes to the oral microbiome, inflammatory mediators, gingival health indices and to assess oral tolerance after 4 weeks of twice daily use of differing oral hygiene regimens including mouthwash compared to a control group. A follow-up assessment will be completed 2 weeks after cessation of treatments.
Primary Outcome
Microbiome analysis will be conducted by ADA-Forsyth's Oral Microbiome Core.
Interventions
- OTHER Distilled Water
- OTHER Marketed Comparator 1
- OTHER Marketed Comparator 2
- OTHER Prototype Rinse 1
- OTHER Prototype Rinse 2
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2026-02-26 |
| Est. Completion | 2026-05-05 |
| Phase | NA |
What NCT07501455 shows while recruiting
NCT07501455 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 5 interventions - of which Distilled Water is the first listed.
NCT07501455 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07501455 about?
NCT07501455 is a clinical study titled "Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis". This study is a six-week, double-blind, randomized, parallel-group controlled clinical study. The objective of this study is to evaluate the changes to the oral microbiome, inflammatory mediators, gingival health indices and to assess oral tolerance after 4 weeks of twice daily use of differing oral...
What is the current status of trial NCT07501455?
This trial is currently recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2026-02-26. Estimated completion is 2026-05-05.
What interventions are being tested in trial NCT07501455?
The interventions under investigation include: Distilled Water (OTHER), Marketed Comparator 1 (OTHER), Marketed Comparator 2 (OTHER), Prototype Rinse 1 (OTHER), Prototype Rinse 2 (OTHER).
Who is sponsoring clinical trial NCT07501455?
This trial is sponsored by Kenvue Brands, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07501455's enrollment target sits among peer trials
250 410th of 2000 higher than 1,567 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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