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NCT07498270 · ClinicalTrials.gov registry record · NA

Location- and Frequency-Dependent Effects of Thalamic Temporal Interference Stimulation During Sleep

A NA study, sponsored by University of Wisconsin, Madison.

Recruiting
Registry status
NA
Development phase
24
Enrollment target

NCT07498270: Recruiting NA study, sponsored by University of Wisconsin, Madison.

NCT07498270 is a NA study that is actively recruiting participants, run by University of Wisconsin, Madison. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07498270, a NA study, is actively recruiting participants, sponsored by University of Wisconsin, Madison.

RECRUITING
Registry status
NA
Development phase
24 participants
Enrollment target

Study Summary

This study is to find out whether a type of non-invasive electrical brain stimulation called temporal interference transcranial electrical stimulation (TI-TES) can temporarily change brain activity during sleep, especially sleep spindles (brain rhythms in the \~8-16 Hz range). Up to 24 healthy participants in Dane County, Wisconsin will be enrolled for 3 overnight study visits. Participants can expect to be on study for approximately 5 weeks, depending on scheduling availability.

Primary Outcome

Comparing active TI-TES vs carrier only SHAM, evaluated using both STIM-PRE and POST-PRE contrasts.

Interventions

  • OTHER Magnetic Resonance Imaging (MRI)
  • DEVICE Broad thalamic stimulation (TI-TES)
  • DEVICE Carrier only SHAM stimulation
  • DEVICE Anterior thalamic stimulation (TI-TES)
  • DEVICE Posterior thalamic stimulation (TI-TES)

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2026-06-05
Est. Completion 2028-02
Phase NA
University of Wisconsin, Madison

1,039 total trials

What NCT07498270 shows while recruiting

NCT07498270 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 5 interventions - of which Magnetic Resonance Imaging (MRI) is the first listed.

NCT07498270 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07498270 about?

NCT07498270 is a clinical study titled "Location- and Frequency-Dependent Effects of Thalamic Temporal Interference Stimulation During Sleep". This study is to find out whether a type of non-invasive electrical brain stimulation called temporal interference transcranial electrical stimulation (TI-TES) can temporarily change brain activity during sleep, especially sleep spindles (brain rhythms in the \~8-16 Hz range). Up to 24 healthy parti...

What is the current status of trial NCT07498270?

This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2026-06-05. Estimated completion is 2028-02.

What interventions are being tested in trial NCT07498270?

The interventions under investigation include: Magnetic Resonance Imaging (MRI) (OTHER), Broad thalamic stimulation (TI-TES) (DEVICE), Carrier only SHAM stimulation (DEVICE), Anterior thalamic stimulation (TI-TES) (DEVICE), Posterior thalamic stimulation (TI-TES) (DEVICE).

Who is sponsoring clinical trial NCT07498270?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07498270's enrollment target sits among peer trials

24 1736th of 2000 higher than 246 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07498270, the US trial registry maintained by the National Library of Medicine. NCT07498270 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.