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NCT07487831 · ClinicalTrials.gov registry record · Phase 4

The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease

A Phase 4 study, sponsored by University of California, San Francisco.

Not yet
Registry status
Phase 4
Development phase
50
Enrollment target

NCT07487831: Clinical Trial Phase 4 study, sponsored by University of California, San Francisco.

NCT07487831 is a Phase 4 study that has not yet begun recruiting, run by University of California, San Francisco. The registered enrollment target is 50 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07487831, a Phase 4 study, has not yet begun recruiting, sponsored by University of California, San Francisco.

NOT YET RECRUITING
Registry status
Phase 4
Development phase
50 participants
Enrollment target

Study Summary

The goal of this clinical trial is to demonstrate the feasibility of a trial that examines the impact of changes in dietary sodium intake on skin sodium levels, atopic dermatitis, and psoriasis. In addition, it aims to generate preliminary data to begin to answer the following questions: 1. Is there an association between skin sodium concentration and atopic dermatitis and psoriasis severity? 2. Are changes in dietary sodium are associated with changes in skin sodium concentration and atopic dermatitis and psoriasis severity? Researchers will compare sodium tablets to a placebo (a look-alike substance that contains no drug) to specifically examine the impact of altering sodium intake. Participants will: * Follow a low-salt diet for the duration of the 13-week study * Take sodium chloride tablets every day for 5 weeks followed by a placebo every day for 5 weeks after a 2-week washout period, or vice versa * Visit the clinic up to 4 times to answer questionnaires, provide bio samples, complete dietary recalls, and undergo non-contrast sodium MRI

Primary Outcome

Fidelity of the low-salt diet and sodium tab intervention adherence will be assessed based on sodium levels from food recall questionnaires and 24-hour urine sodium samples.

Interventions

  • OTHER Placebo Tablets
  • DRUG Sodium chloride tablets

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2026-06-22
Est. Completion 2028-03-17
Phase Phase 4

What is known before NCT07487831 opens enrollment

NCT07487831 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo Tablets is the first listed.

NCT07487831 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07487831 about?

NCT07487831 is a clinical study titled "The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease". The goal of this clinical trial is to demonstrate the feasibility of a trial that examines the impact of changes in dietary sodium intake on skin sodium levels, atopic dermatitis, and psoriasis. In addition, it aims to generate preliminary data to begin to answer the following questions: 1. Is ther...

What is the current status of trial NCT07487831?

This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2026-06-22. Estimated completion is 2028-03-17.

What interventions are being tested in trial NCT07487831?

The interventions under investigation include: Placebo Tablets (OTHER), Sodium chloride tablets (DRUG).

Who is sponsoring clinical trial NCT07487831?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07487831's enrollment target sits among peer trials

50 1255th of 2000 higher than 678 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07487831, the US trial registry maintained by the National Library of Medicine. NCT07487831 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.