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NCT07486934 · ClinicalTrials.gov registry record · Phase 3

Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

A Phase 3 study, sponsored by Dyne Therapeutics.

Recruiting
Registry status
Phase 3
Development phase
150
Enrollment target

NCT07486934 is a Phase 3 study that is actively recruiting participants, run by Dyne Therapeutics. The registered enrollment target is 150 participants.

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The verdict

NCT07486934, a Phase 3 study, is actively recruiting participants, sponsored by Dyne Therapeutics.

RECRUITING
Registry status
Phase 3
Development phase
150 participants
Enrollment target

Study Summary

The purpose of the study is to assess the efficacy, safety, and tolerability of zeleciment basivarsen (DYNE-101) for the treatment of myotonic dystrophy 1 (DM1).

Interventions

  • DRUG Placebo
  • DRUG zeleciment basivarsen (DYNE-101)

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2026-05-14
Est. Completion 2029-01
Phase Phase 3

Sponsor

Dyne Therapeutics

4 total trials

What the Registry Record Tells You About NCT07486934

The ClinicalTrials.gov registry entry for NCT07486934 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Dyne Therapeutics, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT07486934 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07486934 about?

NCT07486934 is a clinical study titled "Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1". The purpose of the study is to assess the efficacy, safety, and tolerability of zeleciment basivarsen (DYNE-101) for the treatment of myotonic dystrophy 1 (DM1).

What is the current status of trial NCT07486934?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 150 participants. The study started on 2026-05-14. Estimated completion is 2029-01.

What interventions are being tested in trial NCT07486934?

The interventions under investigation include: Placebo (DRUG), zeleciment basivarsen (DYNE-101) (DRUG).

Who is sponsoring clinical trial NCT07486934?

This trial is sponsored by Dyne Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.