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NCT07484217 · ClinicalTrials.gov registry record · Phase 3
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
A Phase 3 study of Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms, sponsored by Axsome Therapeutics.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 508
- Enrollment target
- 13
- Study locations
NCT07484217: Recruiting Phase 3 study of Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms, sponsored by Axsome Therapeutics.
NCT07484217 is a Phase 3 study of Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms that is actively recruiting participants, run by Axsome Therapeutics. The registered enrollment target is 508 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (34% lower). The trial reports 13 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07484217, a Phase 3 study of Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms, is actively recruiting participants, sponsored by Axsome Therapeutics.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 508 participants
- Enrollment target
- 13
- Study locations
Study Summary
CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter randomized withdrawal trial in patients with major depressive disorder (MDD) with excessive daytime sleepiness (EDS) symptoms consisting of an open-label solriamfetol treatment period and a randomized, double-blind treatment period.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Solriamfetol 150 MG
Study Locations (13)
California
- Clinical Research Site - Chino
- Clinical Research Site - Redlands
- Clinical Research Site - Walnut Creek
Florida
- Clinical Research Site - Jacksonville
- Clinical Research Site - Miami
New Jersey
- Clinical Research Site - Cherry Hill
- Clinical Research Site - Toms River
New York
- Clinical Research Site - Brooklyn
- Clinical Research Site - The Bronx
Ohio
- Clinical Research Site - Cincinnati
Oregon
- Clinical Research Site - Portland
Tennessee
- Clinical Research Site - Memphis
Texas
- Clinical Research Site - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 508 participants |
| Start Date | 2026-02-23 |
| Est. Completion | 2028-12 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07484217
The ClinicalTrials.gov registry entry for NCT07484217 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 508 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (34% lower). The listed sponsor is Axsome Therapeutics, which has 28 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07484217 reports 13 study locations spanning 8 distinct geographic areas - top geographies include California, Florida, New Jersey.
Frequently Asked Questions
What is clinical trial NCT07484217 about?
NCT07484217 is a clinical study titled "Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol". CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter randomized withdrawal trial in patients with major depressive disorder (MDD) with excessive daytime sleepiness (EDS) symptom...
What is the current status of trial NCT07484217?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 508 participants. The study started on 2026-02-23. Estimated completion is 2028-12.
What conditions does trial NCT07484217 study?
This clinical trial studies the following conditions: Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms.
What interventions are being tested in trial NCT07484217?
The interventions under investigation include: Placebo (DRUG), Solriamfetol 150 MG (DRUG).
Who is sponsoring clinical trial NCT07484217?
This trial is sponsored by Axsome Therapeutics, which has 28 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07484217 being conducted?
This trial has 13 study locations across California, Florida, New Jersey, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.