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NCT07481708 · ClinicalTrials.gov registry record · Phase 1

A Clinical Study of the Effect of Enlicitide (MK-0616) Formulations in Healthy Participants (MK-0616-041)

A Phase 1 study, sponsored by Merck Sharp & Dohme.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target

NCT07481708: Completed Phase 1 study, sponsored by Merck Sharp & Dohme.

NCT07481708 is a Phase 1 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07481708, a Phase 1 study, has completed, sponsored by Merck Sharp & Dohme.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

The goal of this study is to learn what happens to enlicitide (MK-0616) in a healthy person's body over time (pharmacokinetic or PK study). Researchers also want to learn about the safety of enlicitide and if people tolerate it.

Primary Outcome

Blood samples will be collected to determine the AUC0-Last of enlicitide.

Interventions

  • DRUG Enlicitide

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2026-03-23
Est. Completion 2026-05-25
Phase Phase 1
Merck Sharp & Dohme

558 total trials

What the finished NCT07481708 record still lists

NCT07481708 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 1 intervention - of which Enlicitide is the first listed.

NCT07481708 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07481708 about?

NCT07481708 is a clinical study titled "A Clinical Study of the Effect of Enlicitide (MK-0616) Formulations in Healthy Participants (MK-0616-041)". The goal of this study is to learn what happens to enlicitide (MK-0616) in a healthy person's body over time (pharmacokinetic or PK study). Researchers also want to learn about the safety of enlicitide and if people tolerate it.

What is the current status of trial NCT07481708?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2026-03-23. Estimated completion is 2026-05-25.

What interventions are being tested in trial NCT07481708?

The interventions under investigation include: Enlicitide (DRUG).

Who is sponsoring clinical trial NCT07481708?

This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07481708's enrollment target sits among peer trials

30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07481708, the US trial registry maintained by the National Library of Medicine. NCT07481708 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.