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NCT07481214 · ClinicalTrials.gov registry record · NA
Lupus Walking Intervention to Address Fatigue/Quality of Life
A NA study of System Lupus Erythematosus(SLE), sponsored by University of California, San Francisco.
- Completed
- Registry status
- NA
- Development phase
- 101
- Enrollment target
- 1
- Study location
NCT07481214: Completed NA study of System Lupus Erythematosus(SLE), sponsored by University of California, San Francisco.
NCT07481214 is a NA study of System Lupus Erythematosus(SLE) that has completed, run by University of California, San Francisco. The registered enrollment target is 101 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07481214, a NA study of System Lupus Erythematosus(SLE), has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- NA
- Development phase
- 101 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Fatigue is a major concern to individuals with lupus, persisting even when disease activity is clinically minimal, and impacting almost all quality of life domains. Studies show cross-sectional correlations between fatigue and physical activity levels in lupus. Some previous physical activity interventions have been tested in lupus and shown modest, although inconsistent, effects on fatigue. However, all of these interventions have been resource-intensive, requiring structured activities or special facilities, increasing barriers to access, dissemination, and widespread implementation. Focus Area: Improving quality of life for individuals living with lupus, with emphasis on symptom control and challenges that when addressed make day-to-day living with lupus easier and life more fulfilling. Objective and Hypotheses: The proposed study will test a simple pedometer-based walking intervention, based on an intervention previously implemented in rheumatoid arthritis with successful results in reducing fatigue. The intervention will address weaknesses in previous physical activity interventions in lupus that may have limited their impact. Hypothesis 1: Individuals in the intervention arm will achieve greater increases in physical activity than individuals in the control group. Hypothesis 2a: Individuals in the intervention arm will experience greater reductions in fatigue compared to baseline than the control group. Hypothesis 2b: Individuals in the intervention arm will experience greater improvements in other domains of quality of life (e.g., pain interference, perceived cognitive function, sleep disturbance, depression, anxiety) compared to baseline than the control group Hypothesis 2c: Greater increases in activity will be associated with greater reductions in fatigue and improvements in other domains of quality of life. Specific Aims Aim 1: Test the impact of a pedometer-based physical activity intervention on activity levels in persons with systemic
Primary Outcome
The Actigraph will provide step and activity data for 7 days at baseline, midpoint, and the final week of monitoring. These data will be aggregated to calculate an average number of steps/day and average daily time in moderate or vigorous activity, which will be used will be used as the primary measures of physical activity. The Actigraph also yields sedentary time, which can be used as a secondary measure of activity
Conditions Studied
Interventions
- BEHAVIORAL guided increases in daily walking
Study Locations (1)
California
- University of California San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101 participants |
| Start Date | 2022-07-01 |
| Est. Completion | 2025-12-15 |
| Phase | NA |
What the finished NCT07481214 record still lists
NCT07481214 is an interventional study that assigns participants to a tested intervention. The registered 101 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 1 condition, with System Lupus Erythematosus(SLE) appearing as the primary indexed condition, and to 1 intervention - of which guided increases in daily walking is the first listed.
NCT07481214 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT07481214 about?
NCT07481214 is a clinical study titled "Lupus Walking Intervention to Address Fatigue/Quality of Life". Background: Fatigue is a major concern to individuals with lupus, persisting even when disease activity is clinically minimal, and impacting almost all quality of life domains. Studies show cross-sectional correlations between fatigue and physical activity levels in lupus. Some previous physical act...
What is the current status of trial NCT07481214?
This trial is currently completed. It is a NA study. The enrollment target is 101 participants. The study started on 2022-07-01. Estimated completion is 2025-12-15.
What conditions does trial NCT07481214 study?
This clinical trial studies the following conditions: System Lupus Erythematosus(SLE).
What interventions are being tested in trial NCT07481214?
The interventions under investigation include: guided increases in daily walking (BEHAVIORAL).
Who is sponsoring clinical trial NCT07481214?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07481214 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07481214's enrollment target sits among peer trials
101 840th of 2000 higher than 1,161 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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