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NCT07473544 · ClinicalTrials.gov registry record · NA
Essential Oil Inhalation and Acute Stress Response in Healthy Adults
A NA study, sponsored by dōTERRA International.
- Active
- Registry status
- NA
- Development phase
- 200
- Enrollment target
NCT07473544: Active NA study, sponsored by dōTERRA International.
NCT07473544 is a NA study that is active but no longer recruiting, run by dōTERRA International. The registered enrollment target is 200 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07473544, a NA study, is active but no longer recruiting, sponsored by dōTERRA International.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
Study Summary
This randomized, double-blind, placebo-controlled study evaluates the acute physiological and subjective responses to essential oil inhalation in healthy adults. Participants are assigned to inhale either an essential oil or a placebo via an aroma stick during standardized laboratory procedures designed to induce temporary psychosocial stress (Trier Social Stress Test - Group version) and during a guided relaxation session. Physiological responses, including heart rate, heart rate variability, and electrodermal activity, are measured using a wearable sensor. Subjective stress and affect are assessed using validated questionnaires and visual analog scales. The purpose of this study is to characterize short-term autonomic and self-reported responses associated with essential oil inhalation under controlled experimental conditions. This study is exploratory and is not intended to diagnose, treat, or prevent any medical condition.
Primary Outcome
Area under the curve (AUC) for self-reported stress measured using a Visual Analog Scale (VAS) across baseline, stress induction (Trier Social Stress Test - Group version), and post-stressor recovery periods. The VAS-stress scale ranges from low stress to high stress, with higher scores indicating greater perceived stress.
Interventions
- OTHER Essential Oil Inhalation
- OTHER Placebo Aroma Stick
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2026-03-10 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
What the registry record for NCT07473544 still lists
NCT07473544 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 2 interventions - of which Essential Oil Inhalation is the first listed.
NCT07473544 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07473544 about?
NCT07473544 is a clinical study titled "Essential Oil Inhalation and Acute Stress Response in Healthy Adults". This randomized, double-blind, placebo-controlled study evaluates the acute physiological and subjective responses to essential oil inhalation in healthy adults. Participants are assigned to inhale either an essential oil or a placebo via an aroma stick during standardized laboratory procedures desi...
What is the current status of trial NCT07473544?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2026-03-10. Estimated completion is 2027-12-31.
What interventions are being tested in trial NCT07473544?
The interventions under investigation include: Essential Oil Inhalation (OTHER), Placebo Aroma Stick (OTHER).
Who is sponsoring clinical trial NCT07473544?
This trial is sponsored by dōTERRA International, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07473544's enrollment target sits among peer trials
200 506th of 2000 higher than 1,434 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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