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NCT07470606 · ClinicalTrials.gov registry record · Phase 2

Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain

A Phase 2 study, sponsored by The University of Texas Health Science Center at San Antonio.

Not yet
Registry status
Phase 2
Development phase
108
Enrollment target

NCT07470606: Clinical Trial Phase 2 study, sponsored by The University of Texas Health Science Center at San Antonio.

NCT07470606 is a Phase 2 study that has not yet begun recruiting, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 108 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (19% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07470606, a Phase 2 study, has not yet begun recruiting, sponsored by The University of Texas Health Science Center at San Antonio.

NOT YET RECRUITING
Registry status
Phase 2
Development phase
108 participants
Enrollment target

Study Summary

The study investigators are testing to see if patients receiving radiation treatment for brain cancer along with raloxifene plus memantidine take longer to develop memory issues. The study will include anyone over the age of 18 who will be treated with radiation for brain cancer.

Primary Outcome

MRIs will be used to capture any changes in hippocampal volume

Interventions

  • DRUG Memantine
  • DRUG Raloxifene

Trial Details

FieldValue
Enrollment Target 108 participants
Start Date 2026-03
Est. Completion 2031-03
Phase Phase 2

What is known before NCT07470606 opens enrollment

NCT07470606 is an interventional study that assigns participants to a tested intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (19% lower).

The record links to 0 conditions, and to 2 interventions - of which Memantine is the first listed.

NCT07470606 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07470606 about?

NCT07470606 is a clinical study titled "Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain". The study investigators are testing to see if patients receiving radiation treatment for brain cancer along with raloxifene plus memantidine take longer to develop memory issues. The study will include anyone over the age of 18 who will be treated with radiation for brain cancer.

What is the current status of trial NCT07470606?

This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 108 participants. The study started on 2026-03. Estimated completion is 2031-03.

What interventions are being tested in trial NCT07470606?

The interventions under investigation include: Memantine (DRUG), Raloxifene (DRUG).

Who is sponsoring clinical trial NCT07470606?

This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07470606's enrollment target sits among peer trials

108 640th of 2000 higher than 1,355 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07470606, the US trial registry maintained by the National Library of Medicine. NCT07470606 (mid enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.