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NCT07470099 · ClinicalTrials.gov registry record · NA

The Role of Breathing Perception in Respiratory Control

A NA study, sponsored by Indiana University.

Not yet
Registry status
NA
Development phase
15
Enrollment target

NCT07470099: Clinical Trial NA study, sponsored by Indiana University.

NCT07470099 is a NA study that has not yet begun recruiting, run by Indiana University. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07470099, a NA study, has not yet begun recruiting, sponsored by Indiana University.

NOT YET RECRUITING
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

Warfighters are frequently exposed to environments and life-support systems that increase breathing resistance and the work of breathing (WOB), such as aircraft on-board oxygen generation systems and underwater breathing apparatuses. Elevated WOB then increases the perception of breathing difficulty (dyspnea) and has been associated with impaired cognitive performance, including slower reaction time and reduced accuracy during attention-demanding tasks. These effects are particularly concerning in operational settings that require rapid decision-making and precise motor responses. Despite growing recognition of this issue, critical gaps remain regarding strategies to mitigate the perceptual and cognitive consequences of elevated inspiratory resistance, especially under realistic operational stressors. The objective of this experiment is to determine whether modifying the sensory perception of breathing alters breathing perception and cognitive performance during inspiratory resistance. Auditory feedback of ventilation will be manipulated (normal, reduced, or amplified) to assess whether altering breathing-related sensory input affects breathing perception and cognitive performance without changing mechanical load.

Primary Outcome

Time performance on the Stroop Color-Word Test (min:sec) will be measured every 10 minutes during each breathing task.

Interventions

  • OTHER Ambient Noise
  • OTHER Increased Auditory Feedback
  • OTHER Noise Distraction

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2027-06-01
Est. Completion 2028-09-30
Phase NA
Indiana University

890 total trials

What is known before NCT07470099 opens enrollment

NCT07470099 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 3 interventions - of which Ambient Noise is the first listed.

NCT07470099 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07470099 about?

NCT07470099 is a clinical study titled "The Role of Breathing Perception in Respiratory Control". Warfighters are frequently exposed to environments and life-support systems that increase breathing resistance and the work of breathing (WOB), such as aircraft on-board oxygen generation systems and underwater breathing apparatuses. Elevated WOB then increases the perception of breathing difficulty...

What is the current status of trial NCT07470099?

This trial is currently not yet recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2027-06-01. Estimated completion is 2028-09-30.

What interventions are being tested in trial NCT07470099?

The interventions under investigation include: Ambient Noise (OTHER), Increased Auditory Feedback (OTHER), Noise Distraction (OTHER).

Who is sponsoring clinical trial NCT07470099?

This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07470099's enrollment target sits among peer trials

15 1881st of 2000 higher than 92 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07470099, the US trial registry maintained by the National Library of Medicine. NCT07470099 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.