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NCT07470086 · ClinicalTrials.gov registry record · NA
The Role of Environmental Temperatures in Respiratory Control
A NA study, sponsored by Indiana University.
- Not yet
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT07470086: Clinical Trial NA study, sponsored by Indiana University.
NCT07470086 is a NA study that has not yet begun recruiting, run by Indiana University. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07470086, a NA study, has not yet begun recruiting, sponsored by Indiana University.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
Warfighters are frequently exposed to environments and life-support systems that increase breathing resistance and the work of breathing (WOB), such as aircraft on-board oxygen generation systems and underwater breathing apparatuses. Elevated WOB increases the perception of breathing difficulty (dyspnea) and has been associated with impaired cognitive performance, including slower reaction time and reduced accuracy during attention-demanding tasks. These effects are particularly concerning in operational settings that require rapid decision-making and precise motor responses. Despite growing recognition of this issue, critical gaps remain regarding strategies to mitigate the perceptual and cognitive consequences of elevated inspiratory resistance, especially under realistic operational stressors. The objective of this study is to determine whether exposing individuals to thermal stress alters breathing perception and cognitive performance during inspiratory resistance. Participants will perform inspiratory resistance breathing under thermoneutral, heat, and cold conditions to determine whether thermal stress amplifies WOB, breathing perception, and cognitive impairment.
Primary Outcome
Time performance on the Stroop Color-Word Test (min:sec) will be measured every 45 minutes during each experimental breathing task.
Interventions
- OTHER Thermoneutral temperature environment
- OTHER Cold temperature environment
- OTHER Hot temperature environment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2028-10-01 |
| Est. Completion | 2029-12-31 |
| Phase | NA |
What is known before NCT07470086 opens enrollment
NCT07470086 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 3 interventions - of which Thermoneutral temperature environment is the first listed.
NCT07470086 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07470086 about?
NCT07470086 is a clinical study titled "The Role of Environmental Temperatures in Respiratory Control". Warfighters are frequently exposed to environments and life-support systems that increase breathing resistance and the work of breathing (WOB), such as aircraft on-board oxygen generation systems and underwater breathing apparatuses. Elevated WOB increases the perception of breathing difficulty (dys...
What is the current status of trial NCT07470086?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2028-10-01. Estimated completion is 2029-12-31.
What interventions are being tested in trial NCT07470086?
The interventions under investigation include: Thermoneutral temperature environment (OTHER), Cold temperature environment (OTHER), Hot temperature environment (OTHER).
Who is sponsoring clinical trial NCT07470086?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07470086's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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