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NCT07459504 · ClinicalTrials.gov registry record · Phase 2

SMART Diets for MASLD

A Phase 2 study, sponsored by Michigan State University.

Recruiting
Registry status
Phase 2
Development phase
102
Enrollment target

NCT07459504 is a Phase 2 study that is actively recruiting participants, run by Michigan State University. The registered enrollment target is 102 participants.

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The verdict

NCT07459504, a Phase 2 study, is actively recruiting participants, sponsored by Michigan State University.

RECRUITING
Registry status
Phase 2
Development phase
102 participants
Enrollment target

Study Summary

This phase 2 trial is a single-site sequential, multiple assignment, randomized trial (SMART) to test and construct a high-quality adaptive intervention of essential amino acids (EAA) and/or Low Sugar Diet for children with metabolic dysfunction associated steatotic liver disease (MASLD) and increased cardiometabolic risk. The basis for the trial includes high-quality pilot data in both EAA for hepatic steatosis and a low sugar diet for hepatic steatosis. In the trial, children aged 11-17 years old will be eligible to participate if their BMI is greater than or equal to 95th% at baseline and hepatic steatosis is greater than or equal to 8% at baseline by Magnetic Resonance Imaging Proton Density Fat Fraction (MRI-PDFF) because this is the most common age group diagnosed with metabolic-dysfunction associated steatotic liver disease.

Interventions

  • DRUG Essential Amino Acids Supplementation intervention
  • OTHER Low sugar diet

Trial Details

FieldValue
Enrollment Target 102 participants
Start Date 2026-06
Est. Completion 2030-12-26
Phase Phase 2

Sponsor

Michigan State University

120 total trials

What the Registry Record Tells You About NCT07459504

The ClinicalTrials.gov registry entry for NCT07459504 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 102 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Michigan State University, which has 120 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Essential Amino Acids Supplementation intervention is the first listed.

NCT07459504 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07459504 about?

NCT07459504 is a clinical study titled "SMART Diets for MASLD". This phase 2 trial is a single-site sequential, multiple assignment, randomized trial (SMART) to test and construct a high-quality adaptive intervention of essential amino acids (EAA) and/or Low Sugar Diet for children with metabolic dysfunction associated steatotic liver disease (MASLD) and increas...

What is the current status of trial NCT07459504?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 102 participants. The study started on 2026-06. Estimated completion is 2030-12-26.

What interventions are being tested in trial NCT07459504?

The interventions under investigation include: Essential Amino Acids Supplementation intervention (DRUG), Low sugar diet (OTHER).

Who is sponsoring clinical trial NCT07459504?

This trial is sponsored by Michigan State University, which has 120 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.