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NCT07448038 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

A Phase 2 study, sponsored by Genentech.

Recruiting
Registry status
Phase 2
Development phase
162
Enrollment target

NCT07448038 is a Phase 2 study that is actively recruiting participants, run by Genentech. The registered enrollment target is 162 participants.

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The verdict

NCT07448038, a Phase 2 study, is actively recruiting participants, sponsored by Genentech.

RECRUITING
Registry status
Phase 2
Development phase
162 participants
Enrollment target

Study Summary

The main purpose of the study is to evaluate the efficacy of selnoflast compared with placebo in participants with atherosclerosis, at high-risk for major adverse cardiovascular event (MACE), who are currently on standard-of-care (SOC) therapy.

Interventions

  • DRUG Placebo
  • DRUG Selnoflast

Trial Details

FieldValue
Enrollment Target 162 participants
Start Date 2026-06-05
Est. Completion 2028-02-28
Phase Phase 2

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT07448038

The ClinicalTrials.gov registry entry for NCT07448038 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 162 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT07448038 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07448038 about?

NCT07448038 is a clinical study titled "A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events". The main purpose of the study is to evaluate the efficacy of selnoflast compared with placebo in participants with atherosclerosis, at high-risk for major adverse cardiovascular event (MACE), who are currently on standard-of-care (SOC) therapy.

What is the current status of trial NCT07448038?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 162 participants. The study started on 2026-06-05. Estimated completion is 2028-02-28.

What interventions are being tested in trial NCT07448038?

The interventions under investigation include: Placebo (DRUG), Selnoflast (DRUG).

Who is sponsoring clinical trial NCT07448038?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.