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NCT07445932 · ClinicalTrials.gov registry record · NA
Palliative Care Intervention to Improve Health Related Quality of Life for Patients on Long-Term LVAD Support
A NA study, sponsored by Medstar Health Research Institute.
- Not yet
- Registry status
- NA
- Development phase
- 90
- Enrollment target
NCT07445932: Clinical Trial NA study, sponsored by Medstar Health Research Institute.
NCT07445932 is a NA study that has not yet begun recruiting, run by Medstar Health Research Institute. The registered enrollment target is 90 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07445932, a NA study, has not yet begun recruiting, sponsored by Medstar Health Research Institute.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
Study Summary
Background: While left ventricular assist device (LVAD) therapy improves survival in patients with advanced heart failure (AHF), unique LVAD-related burdens may impact health-related quality of life (HRQoL). Palliative care specialists are key members of the multidisciplinary care team for patients with long-term-LVAD (LT-LVAD), offering specialized, comprehensive, holistic care. Problem: A seminal study of palliative care in patients with heart failure (PAL-HF trial) demonstrated that outpatient palliative care improved HRQoL, depression, anxiety, and spiritual well-being compared to usual care. The impact of longitudinal palliative care on HRQoL in LT-LVAD patients is unknown. Objective: The investigators aim to conduct the first study examining a palliative care intervention to improve HRQoL among LT- LVAD recipients (patients who have lived with LT-LVAD for at least six months and are not heart transplant candidates) at two centers (MedStar Health and Inova) in the Mid-Atlantic Region. Given the demographics of the study institutions, the investigators anticipate a socioeconomically and racially diverse cohort of patients with subgroups who may disproportionately experience LVAD-related burdens relative to benefits. Aims: The first aim is to assess baseline measures of HRQoL in LT-LVAD patients to understand differences in HRQoL across subgroups and multiple, understudied domains. The second aim is to test the feasibility and acceptability of a randomized, unblinded pilot study of a palliative care interdisciplinary intervention in this population. Significance: Results of this study will inform the development of a large randomized controlled trial to test the effectiveness of palliative care intervention in improving HRQoL in LT-LVAD patients. If results are positive, this will revolutionize the post-LVAD treatment paradigm, by making palliative care integration the standard of care for longitudinal LT-LVAD patient management.
Primary Outcome
Number of individuals consenting to enroll in the trial.
Interventions
- BEHAVIORAL Palliative care intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2026-03-01 |
| Est. Completion | 2027-03-01 |
| Phase | NA |
What is known before NCT07445932 opens enrollment
NCT07445932 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 1 intervention - of which Palliative care intervention is the first listed.
NCT07445932 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07445932 about?
NCT07445932 is a clinical study titled "Palliative Care Intervention to Improve Health Related Quality of Life for Patients on Long-Term LVAD Support". Background: While left ventricular assist device (LVAD) therapy improves survival in patients with advanced heart failure (AHF), unique LVAD-related burdens may impact health-related quality of life (HRQoL). Palliative care specialists are key members of the multidisciplinary care team for patients ...
What is the current status of trial NCT07445932?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2026-03-01. Estimated completion is 2027-03-01.
What interventions are being tested in trial NCT07445932?
The interventions under investigation include: Palliative care intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT07445932?
This trial is sponsored by Medstar Health Research Institute, which has 115 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07445932's enrollment target sits among peer trials
90 941st of 2000 higher than 1,029 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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