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NCT07443891 · ClinicalTrials.gov registry record · NA

Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia

A NA study of Laryngeal Dystonia, sponsored by University of Minnesota.

Recruiting
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT07443891: Recruiting NA study of Laryngeal Dystonia, sponsored by University of Minnesota.

NCT07443891 is a NA study of Laryngeal Dystonia that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 20 participants, below the 107-participant average among 9 other Laryngeal Dystonia trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07443891, a NA study of Laryngeal Dystonia, is actively recruiting participants, sponsored by University of Minnesota.

RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

Laryngeal dystonia (LD) is a focal dystonia affecting laryngeal muscles, causing involuntary spasms that impair speech production. Recent research demonstrated that non-invasive vibrotactile stimulation (VTS) of the laryngeal area can provide acute symptom relief in up to 57% of patients, with improvements in voice quality and reductions in perceived speech effort lasting from minutes to several days. However, the neural mechanisms underlying this therapeutic effect and the factors determining individual treatment response remain incompletely understood. The objective is to evaluate the acute effects of VTS on voice and speech parameters in participants with LD while characterizing associated changes in brain resting-state networks using magnetic resonance imaging (MRI).

Primary Outcome

Resting state functional connectivity (rs-fMRI) refers to the brain's activity when a person is not engaged in any specific task. It measures spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, which indicates brain activity. The rs-fMRI will be obtained twice before and after receiving VTS and the change in rs-fMRI will be obtained.

Conditions Studied

Laryngeal Dystonia

Interventions

  • DEVICE Vibrotactile Stimulation (VTS)

Study Locations (1)

Minnesota

  • University of Minnesota - Minneapolis

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-01-14
Est. Completion 2027-02-28
Phase NA
University of Minnesota

966 total trials

What NCT07443891 shows while recruiting

NCT07443891 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 107-participant average among 9 other Laryngeal Dystonia trials with a reported enrollment target (81% lower).

The record links to 1 condition, with Laryngeal Dystonia appearing as the primary indexed condition, and to 1 intervention - of which Vibrotactile Stimulation (VTS) is the first listed.

NCT07443891 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT07443891 about?

NCT07443891 is a clinical study titled "Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia". Laryngeal dystonia (LD) is a focal dystonia affecting laryngeal muscles, causing involuntary spasms that impair speech production. Recent research demonstrated that non-invasive vibrotactile stimulation (VTS) of the laryngeal area can provide acute symptom relief in up to 57% of patients, with impro...

What is the current status of trial NCT07443891?

This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-01-14. Estimated completion is 2027-02-28.

What conditions does trial NCT07443891 study?

This clinical trial studies the following conditions: Laryngeal Dystonia.

What interventions are being tested in trial NCT07443891?

The interventions under investigation include: Vibrotactile Stimulation (VTS) (DEVICE).

Who is sponsoring clinical trial NCT07443891?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07443891 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Laryngeal Dystonia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07443891's enrollment target sits among peer trials

20 7th of 9 higher than 2 of 9 other Laryngeal Dystonia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Laryngeal Dystonia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT07443891

Source: ClinicalTrials.gov NCT07443891, the US trial registry maintained by the National Library of Medicine. NCT07443891 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.