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NCT07441122 · ClinicalTrials.gov registry record · NA

Enhancing Attention in Elderly Using a Brain-Computer-Interface

A NA study, sponsored by University of Texas at Austin.

Recruiting
Registry status
NA
Development phase
100
Enrollment target

NCT07441122: Recruiting NA study, sponsored by University of Texas at Austin.

NCT07441122 is a NA study that is actively recruiting participants, run by University of Texas at Austin. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07441122, a NA study, is actively recruiting participants, sponsored by University of Texas at Austin.

RECRUITING
Registry status
NA
Development phase
100 participants
Enrollment target

Study Summary

Cognitive reserve refers to the brain's ability to maintain cognitive performance despite age-related changes or neuropathology. Enhancing cognitive reserve is thought to delay cognitive decline and improve functional outcomes in aging and neurodegenerative conditions. Attention and memory-related neural processes are considered key contributors to cognitive reserve, yet it remains unclear whether these neural markers can be deliberately strengthened through targeted training and non-invasive interventions. The goal of this clinical study is to investigate whether mindfulness-based meditation and non-invasive brain stimulation can enhance neural markers of attention and memory that serve as proxies for cognitive reserve in cognitively healthy adults and older adults diagnosed with mild cognitive impairment (MCI). Investigators hypothesize that strengthening these neural markers will lead to measurable improvements in cognitive reserve-related functions in both healthy aging and MCI populations. This study further hypothesizes that neural markers of attention can be selectively enhanced using an electroencephalography (EEG)-based brain-computer interface (BCI) combined with non-invasive interventions such as mindfulness-based relaxation or neuromodulation. During the study, participants will perform a computerized memory task while their EEG signals are recorded in real time. A BCI will analyze these signals to decode the presence or absence of the P300 event-related potential, a well-established neural marker of attentional control and cognitive resource allocation. Real-time feedback and intervention will be used to modulate these neural processes with the goal of promoting adaptive changes in attention-related brain activity. By integrating EEG-based decoding, behavioral training, and non-invasive interventions, this study aims to determine whether targeted modulation of attention-related neural activity can support cognitive reserve in aging and mild cognitive

Primary Outcome

This outcome measures whether neural correlates of attentional markers (e.g. amplitude, peak-to-peak, band power and connectivity measures of neural correlates) change across sessions as a result of intervention.

Interventions

  • DEVICE transcranial electrical stimulation
  • BEHAVIORAL Mindfulness Meditation

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2026-07-01
Est. Completion 2029-02-01
Phase NA
University of Texas at Austin

257 total trials

What NCT07441122 shows while recruiting

NCT07441122 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 2 interventions - of which transcranial electrical stimulation is the first listed.

NCT07441122 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07441122 about?

NCT07441122 is a clinical study titled "Enhancing Attention in Elderly Using a Brain-Computer-Interface". Cognitive reserve refers to the brain's ability to maintain cognitive performance despite age-related changes or neuropathology. Enhancing cognitive reserve is thought to delay cognitive decline and improve functional outcomes in aging and neurodegenerative conditions. Attention and memory-related n...

What is the current status of trial NCT07441122?

This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2026-07-01. Estimated completion is 2029-02-01.

What interventions are being tested in trial NCT07441122?

The interventions under investigation include: transcranial electrical stimulation (DEVICE), Mindfulness Meditation (BEHAVIORAL).

Who is sponsoring clinical trial NCT07441122?

This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07441122's enrollment target sits among peer trials

100 840th of 2000 higher than 1,081 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07441122, the US trial registry maintained by the National Library of Medicine. NCT07441122 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.