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NCT07437105 · ClinicalTrials.gov registry record · Phase 1

Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants

A Phase 1 study, sponsored by Vertex Pharmaceuticals Incorporated.

Recruiting
Registry status
Phase 1
Development phase
128
Enrollment target

NCT07437105 is a Phase 1 study that is actively recruiting participants, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 128 participants.

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The verdict

NCT07437105, a Phase 1 study, is actively recruiting participants, sponsored by Vertex Pharmaceuticals Incorporated.

RECRUITING
Registry status
Phase 1
Development phase
128 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of single and multiple ascending doses of VX-272.

Interventions

  • DRUG Placebo
  • DRUG VX-272

Trial Details

FieldValue
Enrollment Target 128 participants
Start Date 2026-02-25
Est. Completion 2027-03-23
Phase Phase 1

Sponsor

Vertex Pharmaceuticals Incorporated

191 total trials

What the Registry Record Tells You About NCT07437105

The ClinicalTrials.gov registry entry for NCT07437105 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 128 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT07437105 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07437105 about?

NCT07437105 is a clinical study titled "Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants". The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of single and multiple ascending doses of VX-272.

What is the current status of trial NCT07437105?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 128 participants. The study started on 2026-02-25. Estimated completion is 2027-03-23.

What interventions are being tested in trial NCT07437105?

The interventions under investigation include: Placebo (DRUG), VX-272 (DRUG).

Who is sponsoring clinical trial NCT07437105?

This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.