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NCT07434492 · ClinicalTrials.gov registry record · Phase 2
Smart AFO and 5-Azacitidine to Enhance Mobility in Children With Cerebral Palsy
A Phase 2 study, sponsored by Shirley Ryan AbilityLab.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
NCT07434492 is a Phase 2 study that is actively recruiting participants, run by Shirley Ryan AbilityLab. The registered enrollment target is 60 participants.
The verdict
NCT07434492, a Phase 2 study, is actively recruiting participants, sponsored by Shirley Ryan AbilityLab.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
Study Summary
This is an intervention study to investigate the impact of a smart ankle-foot orthosis (AFO) on mobility outcomes in children with Cerebral Palsy. Participants will complete a three phase protocol including 6-weeks of at home training with the smart AFO. Participants will also have the option to participate in a randomized control trial to investigate the impact of 5-Azacitidine combined with the smart AFO to further effect mobility outcomes.
Interventions
- DRUG Placebo
- DRUG 5-Azacitidine
- DEVICE Smart Ankle-Foot Orthosis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2026-05-28 |
| Est. Completion | 2030-08-31 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07434492
The ClinicalTrials.gov registry entry for NCT07434492 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shirley Ryan AbilityLab, which has 138 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT07434492 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07434492 about?
NCT07434492 is a clinical study titled "Smart AFO and 5-Azacitidine to Enhance Mobility in Children With Cerebral Palsy". This is an intervention study to investigate the impact of a smart ankle-foot orthosis (AFO) on mobility outcomes in children with Cerebral Palsy. Participants will complete a three phase protocol including 6-weeks of at home training with the smart AFO. Participants will also have the option to par...
What is the current status of trial NCT07434492?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2026-05-28. Estimated completion is 2030-08-31.
What interventions are being tested in trial NCT07434492?
The interventions under investigation include: Placebo (DRUG), 5-Azacitidine (DRUG), Smart Ankle-Foot Orthosis (DEVICE).
Who is sponsoring clinical trial NCT07434492?
This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.
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