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NCT07433959 · ClinicalTrials.gov registry record · NA
Neuromodulation to Improve Grasping Function After SCI
A NA study, sponsored by State University of New York at Buffalo.
- Recruiting
- Registry status
- NA
- Development phase
- 54
- Enrollment target
NCT07433959: Recruiting NA study, sponsored by State University of New York at Buffalo.
NCT07433959 is a NA study that is actively recruiting participants, run by State University of New York at Buffalo. The registered enrollment target is 54 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07433959, a NA study, is actively recruiting participants, sponsored by State University of New York at Buffalo.
- RECRUITING
- Registry status
- NA
- Development phase
- 54 participants
- Enrollment target
Study Summary
The goal of this study is to restore the activities of late descending signals with a noninvasive stimulation approach in combination with hand motor training to improve hand function in persons with cervical SCI. The main question it aims to answer is if the inputs to late descending signals above the level of injury and the output of residual late descending signals below the level of injury could be increased. Specifically, in the first part of the study, 30 participants will complete 2 randomized sessions to compare the effect of intermittent theta burst stimulation combined with paired corticospinal motoneuronal stimulation. In the second part of the study, 24 participants will complete either combined stimulation protocol or sham stimulation protocol with exercise training.
Primary Outcome
Transcranial magnetic stimuli (TMS) will be delivered through a figure-of-eight coil over primary motor cortex to the optimal scalp position for activation of hand muscles. The optimal scalp position will be determined by moving the coil in small steps along the hand representations of the primary motor cortex to find the region where the largest MEP can be evoked with the minimum intensity in the targeted muscle. Twenty MEPs will be collected and the peak-to-peak amplitude of MEP will be averag
Interventions
- BEHAVIORAL Exercise
- OTHER iTBS
- OTHER Sham iTBS
- OTHER PCMS
- OTHER Sham PCMS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2026-04-01 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
What NCT07433959 shows while recruiting
NCT07433959 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 5 interventions - of which Exercise is the first listed.
NCT07433959 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07433959 about?
NCT07433959 is a clinical study titled "Neuromodulation to Improve Grasping Function After SCI". The goal of this study is to restore the activities of late descending signals with a noninvasive stimulation approach in combination with hand motor training to improve hand function in persons with cervical SCI. The main question it aims to answer is if the inputs to late descending signals above ...
What is the current status of trial NCT07433959?
This trial is currently recruiting. It is a NA study. The enrollment target is 54 participants. The study started on 2026-04-01. Estimated completion is 2027-06-30.
What interventions are being tested in trial NCT07433959?
The interventions under investigation include: Exercise (BEHAVIORAL), iTBS (OTHER), Sham iTBS (OTHER), PCMS (OTHER), Sham PCMS (OTHER).
Who is sponsoring clinical trial NCT07433959?
This trial is sponsored by State University of New York at Buffalo, which has 243 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07433959's enrollment target sits among peer trials
54 1268th of 2000 higher than 730 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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