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NCT07426458 · ClinicalTrials.gov registry record · Phase 4
Ventilation and Perfusion in Asthmatics
A Phase 4 study, sponsored by University of Miami.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
NCT07426458: Recruiting Phase 4 study, sponsored by University of Miami.
NCT07426458 is a Phase 4 study that is actively recruiting participants, run by University of Miami. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07426458, a Phase 4 study, is actively recruiting participants, sponsored by University of Miami.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
Study Summary
Assess regional changes to perfusion and ventilation from inhaled corticosteroid (ICS) and Fast-acting beta-antagonist (FABA) among adult asthmatics using radiographically derived estimates of regional ventilation (V-distribution), ventilation defect percentage (VDP), and ventilation heterogeneity (VH).
Primary Outcome
Regional ventilation will be measured using functional lung imaging (XV LVAS) before and after inhalation of Albuterol/Budesonide. The outcome will be defined as the change in voxel-wise ventilation distribution from end expiration to peak inspiration, normalized to regional lung volume.
Interventions
- DRUG Albuterol Sulfate
- DRUG Albuterol-Budesonide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-04-27 |
| Est. Completion | 2028-04 |
| Phase | Phase 4 |
What NCT07426458 shows while recruiting
NCT07426458 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 2 interventions - of which Albuterol Sulfate is the first listed.
NCT07426458 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07426458 about?
NCT07426458 is a clinical study titled "Ventilation and Perfusion in Asthmatics". Assess regional changes to perfusion and ventilation from inhaled corticosteroid (ICS) and Fast-acting beta-antagonist (FABA) among adult asthmatics using radiographically derived estimates of regional ventilation (V-distribution), ventilation defect percentage (VDP), and ventilation heterogeneity (...
What is the current status of trial NCT07426458?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2026-04-27. Estimated completion is 2028-04.
What interventions are being tested in trial NCT07426458?
The interventions under investigation include: Albuterol Sulfate (DRUG), Albuterol-Budesonide (DRUG).
Who is sponsoring clinical trial NCT07426458?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07426458's enrollment target sits among peer trials
40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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