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NCT07426120 · ClinicalTrials.gov registry record · Phase 3
Efficacy and Safety of a Botanical Total Coumarin (TC) Cream in Treating Patients With Psoriasis Vulgaris (PLANTCOAT-III)
A Phase 3 study of Psoriasis Vulgaris and Topical Administration, sponsored by Psoriasis Research Institute of Guangzhou.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 300
- Enrollment target
- 1
- Study location
NCT07426120: Recruiting Phase 3 study of Psoriasis Vulgaris and Topical Administration, sponsored by Psoriasis Research Institute of Guangzhou.
NCT07426120 is a Phase 3 study of Psoriasis Vulgaris and Topical Administration that is actively recruiting participants, run by Psoriasis Research Institute of Guangzhou. The registered enrollment target is 300 participants, above the 42-participant average among 6 other Psoriasis Vulgaris trials with a reported enrollment target (614% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07426120, a Phase 3 study of Psoriasis Vulgaris and Topical Administration, is actively recruiting participants, sponsored by Psoriasis Research Institute of Guangzhou.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn if a botanical Total Coumarin topical cream (TC Cream) works to treat psoriasis in adults. It will also learn about the safety of the topical TC Cream. The main questions it aims to answer are: * Does TC Cream improve the psoriasis disease symptoms? * What medical problems do participants have when applying TC Cream? * Does TC Cream improve the quality of life of psoriasis patients? Researchers will compare TC Cream to a placebo cream (a look-alike cream that contains no active drug) to see if TC Cream works to treat psoriasis. Participants will: * Topically apply the TC Cream or a placebo cream twice daily every day to affected skin for 8 weeks * Visit the clinic once every 2 weeks for checkups and tests * Keep a diary of their symptoms and their diseased skin conditions during the application of the topical cream
Primary Outcome
0-4 scale to measure the global severity of psoriasis. 0-Clear, 1-Almost Clear, 2-Mild, 3-Moderate, 4-Severe
Conditions Studied
Interventions
- DRUG Vehicle cream
- DRUG Total coumarin (TC) cream
Study Locations (1)
New York
- Department of Dermatology, SUNY Downstate Health Sciences University - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2026-02-01 |
| Est. Completion | 2028-06-30 |
| Phase | Phase 3 |
What NCT07426120 shows while recruiting
NCT07426120 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 42-participant average among 6 other Psoriasis Vulgaris trials with a reported enrollment target (614% higher).
The record links to 3 conditions, with Psoriasis Vulgaris appearing as the primary indexed condition, and to 2 interventions - of which Vehicle cream is the first listed.
NCT07426120 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT07426120 about?
NCT07426120 is a clinical study titled "Efficacy and Safety of a Botanical Total Coumarin (TC) Cream in Treating Patients With Psoriasis Vulgaris (PLANTCOAT-III)". The goal of this clinical trial is to learn if a botanical Total Coumarin topical cream (TC Cream) works to treat psoriasis in adults. It will also learn about the safety of the topical TC Cream. The main questions it aims to answer are: * Does TC Cream improve the psoriasis disease symptoms? * Wha...
What is the current status of trial NCT07426120?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 300 participants. The study started on 2026-02-01. Estimated completion is 2028-06-30.
What conditions does trial NCT07426120 study?
This clinical trial studies the following conditions: Psoriasis Vulgaris, Topical Administration, Phase III.
What interventions are being tested in trial NCT07426120?
The interventions under investigation include: Vehicle cream (DRUG), Total coumarin (TC) cream (DRUG).
Who is sponsoring clinical trial NCT07426120?
This trial is sponsored by Psoriasis Research Institute of Guangzhou, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07426120 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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