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NCT07422376 · ClinicalTrials.gov registry record · NA
Evaluation of Scalp Cooling During Chemotherapy on Quality of Life and the Potential Role of Single Nucleotide Variations on Chemotherapy-Induced Alopecia and Hair Regrowth in the Appalachian Highlands Region
A NA study of Alopecia, sponsored by Charles Mays.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT07422376 is a NA study of Alopecia that is actively recruiting participants, run by Charles Mays. The registered enrollment target is 100 participants, below the 117-participant average among 13 other Alopecia trials with a reported enrollment target (15% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07422376, a NA study of Alopecia, is actively recruiting participants, sponsored by Charles Mays.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This single-blind, randomized controlled trial is proposed to assess the effects of the PAXMAN Scalp Cooling System on the quality of life of breast cancer subjects receiving any treatment regimen consisting of a chemotherapy agent known to cause chemotherapy-induced alopecia (CIA). Quality of life will be measured using the Chemotherapy-Induced Alopecia Distress Scale (CADS) for cancer patients pre-and post-treatment. Simultaneously, the effect of scalp cooling on hair retention and regrowth will be determined by self-reported grading of photographic assessment using the Alopecia (Hair Loss) Pictorial Tool. Results will be correlated with presence of single nucleotide variations (SNVs) rs3820706 in the CACNB4 gene and rs1202179 in the ABCB1 gene. Participants will be blinded to genetic results until the completion of the study to prevent bias, as knowing results could influence the participants' behavior.
Conditions Studied
Interventions
- DEVICE Paxman Scalp Cooling System
Study Locations (1)
Tennessee
- Ballad Health Cancer Care - Kingsport
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2026-03-01 |
| Est. Completion | 2027-01-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07422376
The ClinicalTrials.gov registry entry for NCT07422376 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 117-participant average among 13 other Alopecia trials with a reported enrollment target (15% lower). The listed sponsor is Charles Mays, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Alopecia appearing as the primary indexed condition, and to 1 intervention - of which Paxman Scalp Cooling System is the first listed.
NCT07422376 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT07422376 about?
NCT07422376 is a clinical study titled "Evaluation of Scalp Cooling During Chemotherapy on Quality of Life and the Potential Role of Single Nucleotide Variations on Chemotherapy-Induced Alopecia and Hair Regrowth in the Appalachian Highlands Region". This single-blind, randomized controlled trial is proposed to assess the effects of the PAXMAN Scalp Cooling System on the quality of life of breast cancer subjects receiving any treatment regimen consisting of a chemotherapy agent known to cause chemotherapy-induced alopecia (CIA). Quality of life ...
What is the current status of trial NCT07422376?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2026-03-01. Estimated completion is 2027-01-01.
What conditions does trial NCT07422376 study?
This clinical trial studies the following conditions: Alopecia.
What interventions are being tested in trial NCT07422376?
The interventions under investigation include: Paxman Scalp Cooling System (DEVICE).
Who is sponsoring clinical trial NCT07422376?
This trial is sponsored by Charles Mays, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07422376 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Read our methodology - how this data is sourced, computed, and verified.
Related
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