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NCT07418502 · ClinicalTrials.gov registry record · Phase 2
Pressure Targeting During High Flow Therapy in Premature Infants
A Phase 2 study, sponsored by University of Texas at Austin.
- Not yet
- Registry status
- Phase 2
- Development phase
- 78
- Enrollment target
NCT07418502: Clinical Trial Phase 2 study, sponsored by University of Texas at Austin.
NCT07418502 is a Phase 2 study that has not yet begun recruiting, run by University of Texas at Austin. The registered enrollment target is 78 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07418502, a Phase 2 study, has not yet begun recruiting, sponsored by University of Texas at Austin.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 78 participants
- Enrollment target
Study Summary
The goal of this study is to see if a new approach to breathing support ('Pressure Targeted High Flow') is as effective as standard of care ('Continuous Positive Airway Pressure') in prematurely born infants. It will also learn about the effect of these types of breathing support on infant comfort and impact on staffing. The main question it aims to answer is: Does Pressure Targeted High Flow provide enough support in premature infants? Participants will: Take spend 24 hours supported by Pressure Targeted High Flow and 24 hours supported by CPAP. During this time their breathing rate, oxygen requirement and other markers of comfort will be monitored.
Primary Outcome
Failure of respiratory support as defined by increase in fraction of inspired oxygen (FiO2) of ≥0.10, a pH of ≤7.2 with a CO2 ≥60 mm Hg, an increase in transcutaneous CO2 of ≥15mmHg above baseline or ≥2 episodes of apnea requiring positive-pressure ventilation
Interventions
- PROCEDURE CPAP
- PROCEDURE Pressure Targeted High Flow
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 78 participants |
| Start Date | 2026-05-01 |
| Est. Completion | 2027-09 |
| Phase | Phase 2 |
What is known before NCT07418502 opens enrollment
NCT07418502 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 78 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower).
The record links to 0 conditions, and to 2 interventions - of which CPAP is the first listed.
NCT07418502 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07418502 about?
NCT07418502 is a clinical study titled "Pressure Targeting During High Flow Therapy in Premature Infants". The goal of this study is to see if a new approach to breathing support ('Pressure Targeted High Flow') is as effective as standard of care ('Continuous Positive Airway Pressure') in prematurely born infants. It will also learn about the effect of these types of breathing support on infant comfort a...
What is the current status of trial NCT07418502?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 78 participants. The study started on 2026-05-01. Estimated completion is 2027-09.
What interventions are being tested in trial NCT07418502?
The interventions under investigation include: CPAP (PROCEDURE), Pressure Targeted High Flow (PROCEDURE).
Who is sponsoring clinical trial NCT07418502?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07418502's enrollment target sits among peer trials
78 884th of 2000 higher than 1,110 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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