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NCT07416604 · ClinicalTrials.gov registry record · Phase 3
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
A Phase 3 study, sponsored by Hoffmann-La Roche.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 360
- Enrollment target
NCT07416604: Recruiting Phase 3 study, sponsored by Hoffmann-La Roche.
NCT07416604 is a Phase 3 study that is actively recruiting participants, run by Hoffmann-La Roche. The registered enrollment target is 360 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07416604, a Phase 3 study, is actively recruiting participants, sponsored by Hoffmann-La Roche.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 360 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of NXT007 prophylaxis compared with emicizumab prophylaxis in people age 12 years and older with severe or moderate congenital hemophilia A without factor VIII (FVIII) inhibitors or with hemophilia A of any severity (severe, moderate, and mild) with FVIII inhibitors.
Interventions
- DRUG Emicizumab
- COMBINATION_PRODUCT NXT007
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 360 participants |
| Start Date | 2026-04-27 |
| Est. Completion | 2032-01-29 |
| Phase | Phase 3 |
What NCT07416604 shows while recruiting
NCT07416604 is an interventional study that assigns participants to a tested intervention. The registered 360 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 2 interventions - of which Emicizumab is the first listed.
NCT07416604 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07416604 about?
NCT07416604 is a clinical study titled "A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A". The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of NXT007 prophylaxis compared with emicizumab prophylaxis in people age 12 years and older with severe or moderate congenital hemophilia A without factor VIII (FVIII) inhibitors or with hemophilia ...
What is the current status of trial NCT07416604?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 360 participants. The study started on 2026-04-27. Estimated completion is 2032-01-29.
What interventions are being tested in trial NCT07416604?
The interventions under investigation include: Emicizumab (DRUG), NXT007 (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT07416604?
This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07416604's enrollment target sits among peer trials
360 1008th of 2000 higher than 980 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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